databases > DOI:10.25504/FAIRsharing.4bt49f

ready Polymorphism in microRNAs and their TargetSites

Abbreviation:PolymiRTS

General Information
PolymiRTS (Polymorphism in microRNAs and their TargetSites) is a database of naturally occurring DNA variations in microRNA (miRNA) seed regions and miRNA target sites. MicroRNAs pair to the transcripts of protein-coding genes and cause translational repression or mRNA destabilization. SNPs and INDELs in miRNAs and their target sites may affect miRNA-mRNA interaction, and hence affect miRNA-mediated gene repression.

Homepage http://compbio.uthsc.edu/miRSNP/

Countries that developed this resource United States

Created in 2006

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How to cite this record FAIRsharing.org: PolymiRTS; Polymorphism in microRNAs and their TargetSites; DOI: https://doi.org/10.25504/FAIRsharing.4bt49f; Last edited: Jan. 8, 2019, 1:14 p.m.; Last accessed: Oct 22 2020 1:49 a.m.


Record updated: Nov. 21, 2018, 11:46 a.m. by The FAIRsharing Team.

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General

help http://compbio.uthsc.edu/miRSNP/help.php
wikipedia https://en.wikipedia.org/wiki/PolymiRTS

Additional Information

Contact Yan Cui




Publications

PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits.

Bao L., Zhou M., Wu L., Lu L., Goldowitz D., Williams RW., Cui Y.,
Nucleic Acids Res. 2007

View Paper (PubMed) View Publication

PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways.

Bhattacharya A,Ziebarth JD,Cui Y
Nucleic Acids Res 2013

View Paper (PubMed) View Publication

PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits.

Ziebarth JD,Bhattacharya A,Chen A,Cui Y
Nucleic Acids Res 2011

View Paper (PubMed) View Publication

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Grant Number(s)

  • 0830134N (American Heart Association, USA)

  • AA014425 (U.S. National Library of Medicine)

  • AI019782 (U.S. National Library of Medicine)

  • AI081050 (U.S. National Library of Medicine)

  • DA021131 (U.S. National Library of Medicine)

  • HD052472 (U.S. National Library of Medicine)

  • NR009270 (U.S. National Library of Medicine)

  • W81XHW-05-01-0227 (U.S. Department of Defense)