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Polymorphism in microRNAs and their TargetSites

Abbreviation:PolymiRTS

General Information

PolymiRTS (Polymorphism in microRNAs and their TargetSites) is a database of naturally occurring DNA variations in microRNA (miRNA) seed regions and miRNA target sites. MicroRNAs pair to the transcripts of protein-coding genes and cause translational repression or mRNA destabilization. SNPs and INDELs in miRNAs and their target sites may affect miRNA-mRNA interaction, and hence affect miRNA-mediated gene repression.

Homepage http://compbio.uthsc.edu/miRSNP/

Countries that developed this resource United States

Created in 2006

Taxonomic range

Homo sapiens

Mus musculus

Knowledge Domains

Subjects

How to cite this record FAIRsharing.org: PolymiRTS; Polymorphism in microRNAs and their TargetSites; DOI: https://doi.org/10.25504/FAIRsharing.4bt49f; Last edited: May 20, 2021, 1:41 p.m.; Last accessed: Jan 23 2022 12:48 p.m.

Record updated: May 20, 2021, 1:35 p.m. by The FAIRsharing Team.

Show edit history

Edits to 'https://fairsharing.org/FAIRsharing.4bt49f' by 'The FAIRsharing Team' at 13:35, 20 May 2021 (approved):

	'organizations' has been modified:
		Before:
			American Heart Association, USA|http://www.heart.org/|Maintains
			U.S. Department of Defense|http://www.defense.gov/|Funds
			Yan Cui's Lab, University of Tennessee Health Science Center,  Memphis, USA|http://compbio.uthsc.edu/|Maintains
			U.S. National Library of Medicine|https://www.nlm.nih.gov/|Funds
			National Institute on Alcohol Abuse and Alcoholism (NIAAA), Bethesda, MD, USA|https://www.niaaa.nih.gov/|Funds
		After:
			U.S. Department of Defense|http://www.defense.gov/|Funds
			U.S. National Library of Medicine|https://www.nlm.nih.gov/|Funds
			National Institute on Alcohol Abuse and Alcoholism (NIAAA), Bethesda, MD, USA|https://www.niaaa.nih.gov/|Funds
			Yan Cui's Lab, University of Tennessee Health Science Center,  Memphis, USA|http://compbio.uthsc.edu/|Maintains
			American Heart Association, USA|http://www.heart.org/|Maintains,Funds
		Added:
			American Heart Association, USA|http://www.heart.org/|Maintains,Funds
		Removed:
			American Heart Association, USA|http://www.heart.org/|Maintains

	'miriam_id' has been modified:
		Before: None
		After:

Edits to 'https://fairsharing.org/FAIRsharing.4bt49f' by 'The FAIRsharing Team' at 11:46, 21 Nov 2018 (approved):

	'domains' has been modified:
		Before:
			Gene silencing by miRNA (microRNA)
			Life Science
			Micro RNA (miRNA)
		After:
			Gene silencing by miRNA (microRNA)
			Genetic polymorphism
			Life Science
			Micro RNA (miRNA)
		Added:
			Genetic polymorphism
		Removed:

Edits to 'https://fairsharing.org/FAIRsharing.4bt49f' by 'The FAIRsharing Team' at 16:25, 02 Dec 2016 (approved):

	'name' has been modified:
		Before: Polymorphism in microRNAs and their TargetSites Database
		After: Polymorphism in microRNAs and their TargetSites

Edits to 'https://fairsharing.org/FAIRsharing.4bt49f' by 'The FAIRsharing Team' at 13:06, 02 Dec 2016 (approved):

	'contactName' has been modified:
		Before:
			
		After:
			Yan Cui
			Tools have changed: 
			Previous values:
			Chromosome Location Search
			Batch Search
			Search
			New values: 
			Batch Search
			Data processes have changed: 
			Previous values:
			Data download
			New values: 
			Data download
			search
			search
			browse
			Organisations have changed: 
			Previous values:
			NIAAA NIH HHS
			Yan Cui's Lab at University of Tennessee Health Science Center
			New values: 
			NIAAA NIH HHS
			Yan Cui's Lab|University of Tennessee Health Science Center| Memphis|USA
			Related databases have changed: 
			Previous values:
			New values: 
			biodbcore-000569: miRBase Sequence Database
			biodbcore-000438: Database of Single Nucleotide Polymorphism
			Grants have changed: 
			Previous values:
			New values: 
			HD052472
			AA014425
			DA021131
			NR009270
			AI081050
			AI019782
			W81XHW-05-01-0227
			0830134N
		Added:
		Removed:

Support

General

help	http://compbio.uthsc.edu/miRSNP/help.php
wikipedia	https://en.wikipedia.org/wiki/PolymiRTS

Additional Information

Contact

Yan Cui

Tools

Batch Search

http://compbio.uthsc.edu/miRSNP/batchsearch.php

Access / Retrieve Data

Conditions of Use

Data Access

Data download	http://compbio.uthsc.edu/miRSNP/download/
search	http://compbio.uthsc.edu/miRSNP/compare.php
search	http://compbio.uthsc.edu/miRSNP/search.php
browse	http://compbio.uthsc.edu/miRSNP/mainbrowse.php

Publications

PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits.

Bao L., Zhou M., Wu L., Lu L., Goldowitz D., Williams RW., Cui Y.,
Nucleic Acids Res. 2007

View Paper (PubMed) View Publication

PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways.

Bhattacharya A,Ziebarth JD,Cui Y
Nucleic Acids Res 2013

View Paper (PubMed) View Publication

PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits.

Ziebarth JD,Bhattacharya A,Chen A,Cui Y
Nucleic Acids Res 2011

View Paper (PubMed) View Publication

Related Standards

Reporting Guidelines

No guidelines defined

Terminology Artifacts

No semantic standards defined

Models and Formats

No syntax standards defined

Identifier Schemas

No identifier schema standards defined

Metrics

No metrics standards defined

Related Databases

Implementing Policies

This record is not implemented by any policy.

Credit

Record Maintainer

This record is in need of a maintainer. If you login, you'll be able to claim this record.

Funds

U.S. Department of Defense (Government body)
U.S. National Library of Medicine (Government body)
National Institute on Alcohol Abuse and Alcoholism (NIAAA), Bethesda, MD, USA (Government body)
American Heart Association, USA (Consortium)

Maintains

Grant Number(s)

0830134N (American Heart Association, USA)
AA014425 (U.S. National Library of Medicine)
AI019782 (U.S. National Library of Medicine)
AI081050 (U.S. National Library of Medicine)
DA021131 (U.S. National Library of Medicine)
HD052472 (U.S. National Library of Medicine)
NR009270 (U.S. National Library of Medicine)
W81XHW-05-01-0227 (U.S. Department of Defense)

Polymorphism in microRNAs and their TargetSites

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