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ready Protein-ligand affinity change upon mutation


General Information
Platinum is a manually curated, literature-derived database comprising over 1,000 mutations which for the first time associates experimental information on changes in protein-ligand affinity with the three-dimensional structures of the complex.


Countries that developed this resource Australia , Brazil , United Kingdom

Created in 2014

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How to cite this record Platinum; Protein-ligand affinity change upon mutation; DOI:; Last edited: Jan. 8, 2019, 1:21 p.m.; Last accessed: Jan 27 2022 8:40 a.m.

This record is maintained by dpires

Record updated: Jan. 5, 2017, 3:41 p.m. by The FAIRsharing Team.

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Platinum: a database of experimentally measured effects of mutations on structurally defined protein-ligand complexes

Douglas E.V. Pires, Tom L. Blundell and David B. Ascher
Nucleic Acids Research 2015

View Paper (PubMed) View Publication

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  • This record is maintained by dpires



Grant Number(s)

  • APP1072476 (National Health and Medical Research Council (NHMRC), Australia)