databases > DOI:10.25504/FAIRsharing.6c4fvf

ready TDR Targets

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Identification and ranking of targets and bioactive compounds against neglected tropical diseases. TDR Targets integrates chemical and genomic information and allows users to prioritize targets and compounds to develop and repurpose new drugs and chemical tools for human pathogens. The TDR Target Project was started in 2005 after a call for applications was launched by TDR (Special Programme for Research and Training in Tropical Diseases (UNICEF / UNDP / World Bank / WHO, As a result, the TDR Targets Database was established to help develop a portfolio of candidate drug targets for 5 major human pathogens. This shortly turned into a resource for prioritizing targets for neglected tropical diseases. TDR Targets is led and run by the Trypanosomatics group at IIB-UNSAM (Argentina, with help with external collaborators worldwide.

How to cite this record TDR Targets; TDR Targets; DOI:; Last edited: Oct. 22, 2019, 11:07 a.m.; Last accessed: Jan 17 2021 12:15 a.m.

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Record updated: Oct. 21, 2019, 3:34 p.m. by fernan.

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Genomic-scale prioritization of drug targets: the TDR Targets database.

Agüero F., Al-Lazikani B., Aslett M., Berriman M., Buckner FS., Campbell RK., Carmona S., Carruthers IM., Chan AW., Chen F., Crowther GJ., Doyle MA., Hertz-Fowler C., Hopkins AL., McAllister G., Nwaka S., Overington JP., Pain A., Paolini GV., Pieper U., Ralph SA., Riechers A., Roos DS., Sali A., Shanmugam D., Suzuki T., Van Voorhis WC., Verlinde CL.,
Nat Rev Drug Discov 2008

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Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

Crowther GJ., Shanmugam D., Carmona SJ., Doyle MA., Hertz-Fowler C., Berriman M., Nwaka S., Ralph SA., Roos DS., Van Voorhis WC., Agüero F.,
PLoS Negl Trop Dis 2010

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TDR Targets: a chemogenomics resource for neglected diseases.

Magarinos MP,Carmona SJ,Crowther GJ,Ralph SA,Roos DS,Shanmugam D,Van Voorhis WC,Aguero F
Nucleic Acids Res 2011

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Grant Number(s)

  • A50830| (World Health Organization, Special Programme for Research and Training in Tropical Diseases (WHO/TDR))

  • PICT-2010-1479 (Agencia Nacional de Promoci?n Cient?fica (ANPCyT, Argentina))

  • PICT-Glaxo-2013-0067 (Agencia Nacional de Promoci?n Cient?fica (ANPCyT, Argentina))