standards > terminology artifact > DOI:10.25504/FAIRsharing.9y3gv0
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ready Enzyme Structure Function Ontology

Abbreviation: ESFO


General Information
The ESFO provides a new paradigm for organizing enzyme sequence, structure, and function information, whereby specific elements of enzyme sequence and structure are mapped to specific conserved aspects of function, thus facilitating the functional annotation of uncharacterized enzymes. The ESFO helps prevent misannotation by emphasizing annotation of enzymes only at the level of functional granularity warranted by available information. The archive is a static snapshot of the data in the SFLD as of April 2019, and will not be updated



How to cite this record FAIRsharing.org: ESFO; Enzyme Structure Function Ontology; DOI: https://doi.org/10.25504/FAIRsharing.9y3gv0; Last edited: Dec. 18, 2019, 11:16 a.m.; Last accessed: Jul 10 2020 10:22 a.m.

Publication for citation  Biocuration in the structure-function linkage database: the anatomy of a superfamily. Holliday GL,Brown SD,Akiva E,Mischel D,Hicks MA,Morris JH,Huang CC,Meng EC,Pegg SC,Ferrin TE,Babbitt PC; Database (Oxford) ; 2017; 10.1093/database/bax006;


Record added: Oct. 24, 2017, 9:41 a.m.
Record updated: Dec. 16, 2019, 2:01 p.m. by The FAIRsharing Team.

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Publications

Biocuration in the structure-function linkage database: the anatomy of a superfamily.

Holliday GL,Brown SD,Akiva E,Mischel D,Hicks MA,Morris JH,Huang CC,Meng EC,Pegg SC,Ferrin TE,Babbitt PC
Database (Oxford) 2017

View Paper (PubMed) View Publication

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Related Databases (2)
Mechanism, Annotation and Classification in Enzymes
MACiE is an electronic database of well-characterised enzymatic reactions. MACiE is the result of more than three years' collaboration between the Mitchell and Murray-Rust groups in the Unilever Centre and Prof. Janet Thornton at the European Bioinformatics Institute. The database contains the reaction mechanisms for 100 individual enzymes; this includes the overall reactions and the multiple steps that constitute them.

Structure Function Linkage Database Archive
Structure Function Linkage Database (SFLD) is a database of enzymes classified by linking sequences to chemical function. A hierachical systems is used to classify enzymes by family or superfamily other category levels include functional domain, subgroup and suprafamily. The archive does not contain the interactive functionality found in the original SFLD, such as search capabilities. Instead, the archive is a static snapshot of the data in the SFLD as of April 2019, and will not be updated.

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