standards > terminology artifact > DOI:10.25504/FAIRsharing.9y3gv0

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ready Enzyme Structure Function Ontology

Abbreviation: ESFO

General Information
The ESFO provides a new paradigm for organizing enzyme sequence, structure, and function information, whereby specific elements of enzyme sequence and structure are mapped to specific conserved aspects of function, thus facilitating the functional annotation of uncharacterized enzymes. The ESFO helps prevent misannotation by emphasizing annotation of enzymes only at the level of functional granularity warranted by available information.


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Created in 2016

Taxonomic range


How to cite this record ESFO; Enzyme Structure Function Ontology; DOI:; Last edited: Jan. 8, 2019, 1:38 p.m.; Last accessed: Oct 20 2019 1:54 a.m.

Record added: Oct. 24, 2017, 9:41 a.m.
Record updated: Nov. 21, 2018, 10:43 a.m. by The FAIRsharing Team.

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Additional Information

External Links


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Conditions of Use


No publications available

ESFO Ontology Display

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Related Standards

Reporting Guidelines

No guidelines defined

Terminology Artifacts

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Models and Formats

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Identifier Schemas

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Implementing Databases (1)
Sequence Function Linkage Database
Structure Function Linkage Database (SFLD) is a database of enzymes classified by linking sequences to chemical function. A heirachical systems is used to classify enzymes by family or superfamily other category levels include functional domain, subgroup and suprafamily.

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