standards > reporting guideline > DOI:10.25504/FAIRsharing.ap169a

ready Minimal Information Required In the Annotation of Models

Abbreviation: MIRIAM

General Information
The Minimal Information Required In the Annotation of Models (MIRIAM), initiated by the effort, is a set of guidelines for the consistent annotation and curation of computational models in biology. It is suitable for use with any structured format for computational models.

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How to cite this record MIRIAM; Minimal Information Required In the Annotation of Models; DOI:; Last edited: March 3, 2020, 1:49 p.m.; Last accessed: Jun 15 2021 4:15 a.m.

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Record updated: March 3, 2020, 1:46 p.m. by The FAIRsharing Team.

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Additional Information


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Access / Retrieve Data


Minimum information requested in the annotation of biochemical models (MIRIAM).

Nicolas Le Novère, Andrew Finney, Michael Hucka, Upinder S Bhalla, Fabien Campagne, Julio Collado-Vides, Edmund J Crampin, Matt Halstead, Edda Klipp, Pedro Mendes, Poul Nielsen, Herbert Sauro, Bruce Shapiro, Jacky L Snoep, Hugh D Spence, Barry L Wanner
Nat. Biotechnol. 2005

View Paper (PubMed) View Publication and MIRIAM Registry: community resources to provide persistent identification.

Juty N,Le Novere N,Laibe C
Nucleic Acids Res 2011

View Paper (PubMed) View Publication

MIRIAM Resources: tools to generate and resolve robust cross-references in Systems Biology.

Laibe C,Le Novere N
BMC Syst Biol 2007

View Paper (PubMed) View Publication

Related Databases (5) Central Registry
The Central Registry provides the necessary information for the generation and resolution of unique and perennial identifiers for life science data. Those identifiers are both in URI and compact form, and make use of to provide direct access to the identified data records on the Web. Resource maintainers request an prefix for their databases or services.

BioModels is a repository of computational models of biological processes. It allows users to search and retrieve mathematical models published in the literature. Many models are manually curated (to ensure reproducibility) and extensively cross-linked to publicly available reference information.

YEASTNET: A consensus reconstruction of yeast metabolism
This is a portal to the consensus yeast metabolic network as reconstructed from the genome sequence and literature. It is a highly annotated metabolic map of Saccharomyces cerevisiae S288c that is periodically updated by a team of collaborators from various research groups.

JWS Online
JWS Online is a Systems Biology tool for the construction, modification and simulation of kinetic models and for the storage of curated models.

BiGG Models
BiGG Models is a knowledgebase of genome-scale metabolic network reconstructions. BiGG Models integrates more than 70 published genome-scale metabolic networks into a single database with a set of standardized identifiers called BiGG IDs.


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Grant Number(s)

  • BB/E005748/1 (Biotechnology and Biological Sciences Research Council (BBSRC), UK)

  • JPA 1729 (Biotechnology and Biological Sciences Research Council (BBSRC), UK)