Record added: Nov. 27, 2015, 2:05 a.m.
Record updated: Nov. 24, 2017, 7:56 p.m. by The FAIRsharing Team.

Edits to 'https://fairsharing.org/FAIRsharing.bya6z' by 'The FAIRsharing Team' at 13:17, 15 Dec 2016 (approved):

	'description' has been modified:
		Before: SEA (Super-Enhancer Archive, http://sea.edbc.org/) is a web based comprehensive resource focusing on the collection, storage and online analysis of super-enhancers. It focuses on integrating super-enhancers in multiple species and annotating their potential roles in the regulation of cell identity gene expression. The current release of SEA (Nov 2015) incorporates 83,996 super-enhancers computationally or experimentally identified in 134 cell types/tissues/diseases, including human (75,439, three of which were experimentally identified), mouse (5,879, five of which were experimentally identified), Drosophila melanogaster (1,774), and Caenorhabditis elegans (904). To facilitate data extraction, SEA supports multiple search options, including species, genome location, gene name, cell type/tissue, and super-enhancer name. The response provides detailed (epi)genetic information, incorporating cell type specificity, nearby genes, transcriptional factor binding sites, CRISPR-Cas9 target sites, evolutionary conservation, SNPs, H3K27ac, DNA methylation, gene expression, and TF ChIP-seq data. Moreover, analytical tools and a genome browser were developed for users to explore super-enhancers and their roles in defining cell identity and disease processes in depth.
		After: SEA (Super-Enhancer Archive) is a web-based comprehensive resource focusing on the collection, storage and online analysis of super-enhancers. It focuses on integrating super-enhancers in multiple species and annotating their potential roles in the regulation of cell identity gene expression. To facilitate data extraction, SEA supports multiple search options, including species, genome location, gene name, cell type/tissue, and super-enhancer name.  Domain list has changed:  Previous values: Bioinformatics tools and formats|| Database|property|http://bioontology.org/ontologies/BiomedicalResourceOntology.owl#Database Enhancers|| Epigenetics|| Histone modification maps (ChIP-seq)|| Regulation of gene expression|process|http://purl.obolibrary.org/obo/GO_0010468 Taxonomic information|process|http://ontology.neuinfo.org/NIF/DigitalEntities/NIF-Investigation.owl#birnlex_2337 Transcription factor (TF) binding site|| New values:  Bioinformatics tools and formats|| Database|property|http://bioontology.org/ontologies/BiomedicalResourceOntology.owl#Database Enhancers|| Epigenetics|| Histone modification maps (ChIP-seq)|| Regulation of gene expression|process|http://purl.obolibrary.org/obo/GO_0010468 Taxonomic information|process|http://ontology.neuinfo.org/NIF/DigitalEntities/NIF-Investigation.owl#birnlex_2337 Transcription factor (TF) binding site|| Life Science|domain| Genomics|| Support links have changed:  Previous values: http://www.bio-bigdata.com/SEA/contact.html http://www.bio-bigdata.com/SEA/help.html New values:  http://www.bio-bigdata.com/SEA/contact.html http://www.bio-bigdata.com/SEA/help.html http://www.bio-bigdata.com/SEA/docs/ Data processes have changed:  Previous values: New values:  analyze Browse search Browser View Organisations have changed:  Previous values: GCER Lab of Developmental Biology New values:  Group of Computational Epigenetic Research (GCER)|China Lab of Developmental Biology|Harbin Institute of Technology|China College of Bioinformatics Science and Technology|Harbin Medical University|Harbin|China National Natural Science Foundation of China Natural Science Foundation of Heilongjiang Province|China Grants have changed:  Previous values: New values:  2015RAXXJ052 YJSCX201423HYD]