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ready IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors

Abbreviation:IPD-NHKIR

General Information
The IPD-NHKIR database provides a centralised repository for non-human KIR (NHKIR) sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.




How to cite this record FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jul 02 2020 6:56 a.m.

Publication for citation  IPD-IMGT/HLA Database. Robinson J,Barker DJ,Georgiou X,Cooper MA,Flicek P,Marsh SGE; Nucleic Acids Res ; 2019; 10.1093/nar/gkz950;


This record is maintained by jamesran

Record updated: March 3, 2020, 1:22 p.m. by The FAIRsharing Team.

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The IPD Project: a centralised resource for the study of polymorphism in genes of the immune system.

Maccari G,Robinson J,Hammond JA,Marsh SGE
Immunogenetics 2019

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Nomenclature report for killer-cell immunoglobulin-like receptors (KIR) in macaque species: new genes/alleles, renaming recombinant entities and IPD-NHKIR updates.

Bruijnesteijn J,de Groot NG,Otting N,Maccari G,Guethlein LA,Robinson J,Marsh SGE,Walter L,O'Connor DH,Hammond JA,Parham P,Bontrop RE
Immunogenetics 2019

View Paper (PubMed) View Publication

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  • NIH/NCI P01 111412 (U.S. National Library of Medicine)

  • QLRI-CT-200!-01325 (The Fifth Framework Infrastructures program, European Commission)