databases > DOI:10.25504/FAIRsharing.gg60g3
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ready The Improved Database Of Chimeric Transcripts and RNA-Seq Data

Abbreviation:ChiTaRS

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The ESTs and mRNAs from GenBank have been used to identify chimeric RNAs of two or more different genes. By analyzing thousands of chimeric ESTs by RNA sequencing, we found that the expression level of chimeric ESTs is generally low and they are highly tissue specific in normal cells. Here we present the improved version of the ChiTaRS database (ChiTaRS-5.0) with more then (66,243 + 41,584 + 3,052 + 19 + 67 + 20 + 292 + 305) = 111,582 chimeric transcripts in humans, mice, fruit flies, rats, zebrafishes, cows, pigs, and yeast. In the current version we extended the experimental data evidence as well as included a novel type of the sense-antisense chimeric transcripts of the same gene confirmed experimentally by RT-PCR, qPCR, RNA-sequencing and mass-spec peptides. In addition, we collected 23,167 human cancer breakpoints with the expression levels of chimeric RNAs confirmed by the paired-end RNA-sequencing experiments in different tissues in humans, mice and fruit flies.




How to cite this record FAIRsharing.org: ChiTaRS; The Improved Database Of Chimeric Transcripts and RNA-Seq Data; DOI: https://doi.org/10.25504/FAIRsharing.gg60g3; Last edited: May 4, 2021, 8:16 a.m.; Last accessed: Sep 25 2021 2:36 p.m.

Publication for citation  ChiTaRS 5.0: the comprehensive database of chimeric transcripts matched with druggable fusions and 3D chromatin maps Deepak Balamurali, Alessandro Gorohovski, Rajesh Detroja, Vikrant Palande, Dorith Raviv-Shay, Milana Frenkel-Morgenstern; Nucleic Acids Research ; 2019; 10.1093/nar/gkz1025;


This record is maintained by AlessandroGorohovski  ORCID

Record updated: April 27, 2021, 10:33 a.m. by AlessandroGorohovski.

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ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

Milana Frenkel-Morgenstern1, Alessandro Gorohovski, Vincent Lacroix, Mark Rogers, Kristina Ibanez, Cesar Boullosa, Eduardo Andres Leon, Asa Ben-Hur and Alfonso Valencia
Nucleic Acids Research 2012

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ChiTaRS 2.1--an improved database of the chimeric transcripts and RNA-seq data with novel sense-antisense chimeric RNA transcripts.

Frenkel-Morgenstern M,Gorohovski A,Vucenovic D,Maestre L,Valencia A
Nucleic Acids Res 2014

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ChiTaRS-3.1-the enhanced chimeric transcripts and RNA-seq database matched with protein-protein interactions.

Gorohovski A,Tagore S,Palande V,Malka A,Raviv-Shay D,Frenkel-Morgenstern M
Nucleic Acids Res 2016

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ChiTaRS 5.0: the comprehensive database of chimeric transcripts matched with druggable fusions and 3D chromatin maps

Deepak Balamurali, Alessandro Gorohovski, Rajesh Detroja, Vikrant Palande, Dorith Raviv-Shay, Milana Frenkel-Morgenstern
Nucleic Acids Research 2019

View Paper (PubMed) View Publication

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