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IPD-KIR - Killer-cell Immunoglobulin-like Receptors

Abbreviation:IPD-KIR

General Information

The database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.

Homepage http://www.ebi.ac.uk/ipd/kir/

Countries that developed this resource United Kingdom , United States

Created in 2003

Taxonomic range

Homo sapiens

Knowledge Domains

Subjects

How to cite this record FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Oct 17 2021 2 a.m.

This record is maintained by jamesran

Record updated: June 15, 2021, 1:58 p.m. by The FAIRsharing Team.

Show edit history

Edits to 'https://fairsharing.org/FAIRsharing.h87prx' by 'The FAIRsharing Team' at 13:58, 15 Jun 2021 (not approved):

	'miriam_id' has been modified:
		Before: 
		After: None

Edits to 'https://fairsharing.org/FAIRsharing.h87prx' by 'jamesran' at 11:45, 15 Jun 2021 (approved):

	'countries' has been modified:
		Before:
			Austria
			Belgium
			Croatia
			Czech Republic
			Denmark
			Finland
			France
			Germany
			Greece
			Hungary
			Iceland
			Israel
			Italy
			Lithuania
			Luxembourg
			Malta
			Montenegro
			Netherlands
			Norway
			Portugal
			Republic of Ireland
			Slovakia
			Spain
			Sweden
			Switzerland
			United Kingdom
			United States
		After:
			United Kingdom
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			Austria
			Belgium
			Croatia
			Czech Republic
			Denmark
			Finland
			France
			Germany
			Greece
			Hungary
			Iceland
			Israel
			Italy
			Lithuania
			Luxembourg
			Malta
			Montenegro
			Netherlands
			Norway
			Portugal
			Republic of Ireland
			Slovakia
			Spain
			Sweden
			Switzerland

Edits to 'https://fairsharing.org/FAIRsharing.h87prx' by 'The FAIRsharing Team' at 11:51, 24 Feb 2020 (approved):

	'countries' has been modified:
		Before:
		After:
			Austria
			Belgium
			Croatia
			Czech Republic
			Denmark
			Finland
			France
			Germany
			Greece
			Hungary
			Iceland
			Israel
			Italy
			Lithuania
			Luxembourg
			Malta
			Montenegro
			Netherlands
			Norway
			Portugal
			Republic of Ireland
			Slovakia
			Spain
			Sweden
			Switzerland
			United Kingdom
			United States
		Added:
			Austria
			Belgium
			Croatia
			Czech Republic
			Denmark
			Finland
			France
			Germany
			Greece
			Hungary
			Iceland
			Israel
			Italy
			Lithuania
			Luxembourg
			Malta
			Montenegro
			Netherlands
			Norway
			Portugal
			Republic of Ireland
			Slovakia
			Spain
			Sweden
			Switzerland
			United Kingdom
			United States
		Removed:

Edits to 'https://fairsharing.org/FAIRsharing.h87prx' by 'The FAIRsharing Team' at 13:55, 21 Feb 2020 (approved):

	'countries' has been modified:
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			United Kingdom
			United States
		After:
		Added:
		Removed:
			United Kingdom
			United States

Edits to 'https://fairsharing.org/FAIRsharing.h87prx' by 'jamesran' at 11:24, 21 Feb 2020 (approved):

	'name' has been modified:
		Before: Killer-cell Immunoglobulin-like Receptors
		After: IPD-KIR - Killer-cell Immunoglobulin-like Receptors

	'countries' has been modified:
		Before:
			Austria
			Belgium
			Croatia
			Czech Republic
			Denmark
			Finland
			France
			Germany
			Greece
			Hungary
			Iceland
			Israel
			Italy
			Lithuania
			Luxembourg
			Malta
			Montenegro
			Netherlands
			Norway
			Portugal
			Republic of Ireland
			Slovakia
			Spain
			Sweden
			Switzerland
			United Kingdom
		After:
			United Kingdom
			United States
		Added:
			United States
		Removed:
			Austria
			Belgium
			Croatia
			Czech Republic
			Denmark
			Finland
			France
			Germany
			Greece
			Hungary
			Iceland
			Israel
			Italy
			Lithuania
			Luxembourg
			Malta
			Montenegro
			Netherlands
			Norway
			Portugal
			Republic of Ireland
			Slovakia
			Spain
			Sweden
			Switzerland

Edits to 'https://fairsharing.org/FAIRsharing.h87prx' by 'The FAIRsharing Team' at 18:07, 10 Feb 2020 (approved):

	'supportLinks' has been modified:
		Before:
			FAQ|https://www.ebi.ac.uk/ipd/kir/faq.html
			contact form|https://www.ebi.ac.uk/support/ipd.php
			online documentation|https://www.ebi.ac.uk/ipd/kir/genes.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/haplotypes.html
			online documentation|https://github.com/ANHIG/IPDKIR
			online documentation|https://www.ebi.ac.uk/ipd/kir/stats.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/nomenclature.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/alleles.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/genotypes.html
		After:
			FAQ|https://www.ebi.ac.uk/ipd/kir/faq.html
			contact form|https://www.ebi.ac.uk/support/hla.php
			online documentation|https://www.ebi.ac.uk/ipd/kir/genes.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/haplotypes.html
			online documentation|https://github.com/ANHIG/IPDKIR
			online documentation|https://www.ebi.ac.uk/ipd/kir/stats.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/nomenclature.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/alleles.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/genotypes.html
		Added:
			contact form|https://www.ebi.ac.uk/support/hla.php
		Removed:
			contact form|https://www.ebi.ac.uk/support/ipd.php

	'description' has been modified:
		Before: The database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors.
		After: The database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.

	'countries' has been modified:
		Before:
			European Union
		After:
			Austria
			Belgium
			Croatia
			Czech Republic
			Denmark
			Finland
			France
			Germany
			Greece
			Hungary
			Iceland
			Israel
			Italy
			Lithuania
			Luxembourg
			Malta
			Montenegro
			Netherlands
			Norway
			Portugal
			Republic of Ireland
			Slovakia
			Spain
			Sweden
			Switzerland
			United Kingdom
		Added:
			Austria
			Belgium
			Croatia
			Czech Republic
			Denmark
			Finland
			France
			Germany
			Greece
			Hungary
			Iceland
			Israel
			Italy
			Lithuania
			Luxembourg
			Malta
			Montenegro
			Netherlands
			Norway
			Portugal
			Republic of Ireland
			Slovakia
			Spain
			Sweden
			Switzerland
			United Kingdom
		Removed:
			European Union

	'yearOfCreation' has been modified:
		Before: 2008
		After: 2003

	'onto_disciplines' has been modified:
		Before:
			Life Science
		After:
			Immunogenetics
			Immunology
		Added:
			Immunogenetics
			Immunology
		Removed:
			Life Science

	'dataProcesses' has been modified:
		Before:
			Download
			submit
		After:
			Download
			Submit
			Browse Fully Sequenced Haplotypes
			Search Probes and Primers
			Cell Queries
		Added:
			Submit
			Browse Fully Sequenced Haplotypes
			Search Probes and Primers
			Cell Queries
		Removed:
			submit

	'tools' has been modified:
		Before:
			KIR Alignment Tool||https://www.ebi.ac.uk/ipd/kir/align.html
			BLAST||https://www.ebi.ac.uk/ipd/kir/blast.html
			KIR Ligand Calculator||https://www.ebi.ac.uk/ipd/kir/ligand.html
			Cell Queries||https://www.ebi.ac.uk/ipd/kir/cell_query.html
		After:
			KIR Alignment Tool||https://www.ebi.ac.uk/ipd/kir/align.html
			BLAST||https://www.ebi.ac.uk/ipd/kir/blast.html
			KIR Ligand Calculator||https://www.ebi.ac.uk/ipd/kir/ligand.html
			Donor KIR B-content group calculator||https://www.ebi.ac.uk/ipd/kir/donor_b_content.html
			IPD-KIR Allele Ethnicity Tool ||https://www.ebi.ac.uk/ipd/kir/ethnicity.html
		Added:
			Donor KIR B-content group calculator||https://www.ebi.ac.uk/ipd/kir/donor_b_content.html
			IPD-KIR Allele Ethnicity Tool ||https://www.ebi.ac.uk/ipd/kir/ethnicity.html
		Removed:
			Cell Queries||https://www.ebi.ac.uk/ipd/kir/cell_query.html

Edits to 'https://fairsharing.org/FAIRsharing.h87prx' by 'The FAIRsharing Team' at 12:47, 14 Jan 2019 (approved):

	'related_databases' has been modified:
		Before:
			ImMunoGeneTics Human Leukocyte Antigen Sequence Database
			Immuno-Polymorphism Database
			Major Histocompatibility Complex Database
		After:
			ImMunoGeneTics Human Leukocyte Antigen Sequence Database
			Immuno-Polymorphism Database
			The European Searchable Tumour Line Database
			Human Platelet Antigens
			Major Histocompatibility Complex Database
		Added:
			The European Searchable Tumour Line Database
			Human Platelet Antigens
		Removed:

Edits to 'https://fairsharing.org/FAIRsharing.h87prx' by 'The FAIRsharing Team' at 13:25, 10 Jan 2019 (approved):

	'organizations' has been modified:
		Before:
			Swiss Institute of Bioinformatics (SIB), Switzerland|https://www.sib.swiss|Maintains
		After:
			Anthony Nolan Research Institute, London, UK|https://www.anthonynolan.org/|Maintains
			Stanford University School of Medicine, CA, USA|http://www.med.stanford.edu|Maintains
			University of Minnesota|https://twin-cities.umn.edu|Maintains
			European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, UK|https://www.ebi.ac.uk/|Maintains
			National Institutes of Health (NIH), Bethesda, MD, USA|http://www.nih.gov|Funds
		Added:
			Anthony Nolan Research Institute, London, UK|https://www.anthonynolan.org/|Maintains
			Stanford University School of Medicine, CA, USA|http://www.med.stanford.edu|Maintains
			University of Minnesota|https://twin-cities.umn.edu|Maintains
			European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, UK|https://www.ebi.ac.uk/|Maintains
			National Institutes of Health (NIH), Bethesda, MD, USA|http://www.nih.gov|Funds
		Removed:
			Swiss Institute of Bioinformatics (SIB), Switzerland|https://www.sib.swiss|Maintains

	'supportLinks' has been modified:
		Before:
			FAQ|http://www.ebi.ac.uk/ipd/kir/faq.html
			contact form|http://www.ebi.ac.uk/support/ipd.php
		After:
			FAQ|https://www.ebi.ac.uk/ipd/kir/faq.html
			contact form|http://www.ebi.ac.uk/support/ipd.php
			online documentation|https://www.ebi.ac.uk/ipd/kir/genes.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/haplotypes.html
			online documentation|https://github.com/ANHIG/IPDKIR
			online documentation|https://www.ebi.ac.uk/ipd/kir/stats.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/nomenclature.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/alleles.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/genotypes.html
		Added:
			FAQ|https://www.ebi.ac.uk/ipd/kir/faq.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/genes.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/haplotypes.html
			online documentation|https://github.com/ANHIG/IPDKIR
			online documentation|https://www.ebi.ac.uk/ipd/kir/stats.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/nomenclature.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/alleles.html
			online documentation|https://www.ebi.ac.uk/ipd/kir/genotypes.html
		Removed:
			FAQ|http://www.ebi.ac.uk/ipd/kir/faq.html

	'licences' has been modified:
		Before:
			Creative Commons Attribution-NoDerivs 3.0 Unported (CC BY-ND 3.0)|https://creativecommons.org/licenses/by-nd/3.0/|Data
		After:
			Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)|https://creativecommons.org/licenses/by-nd/4.0/|Data
		Added:
			Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)|https://creativecommons.org/licenses/by-nd/4.0/|Data
		Removed:
			Creative Commons Attribution-NoDerivs 3.0 Unported (CC BY-ND 3.0)|https://creativecommons.org/licenses/by-nd/3.0/|Data

	'onto_domains' has been modified:
		Before:
			Receptors, KIR
			deoxyribonucleic acid
			protein
		After:
			Nucleic acid sequence
			Receptors, KIR
			deoxyribonucleic acid
			protein
		Added:
			Nucleic acid sequence
		Removed:

	'grants' has been modified:
		Before:
		After:
			P01-CA-111412
		Added:
			P01-CA-111412
		Removed:

	'miriam_id' has been modified:
		Before: None
		After: 

	'tools' has been modified:
		Before:
		After:
			KIR Alignment Tool||https://www.ebi.ac.uk/ipd/kir/align.html
			BLAST||https://www.ebi.ac.uk/ipd/kir/blast.html
			KIR Ligand Calculator||https://www.ebi.ac.uk/ipd/kir/ligand.html
			Cell Queries||https://www.ebi.ac.uk/ipd/kir/cell_query.html
		Added:
			KIR Alignment Tool||https://www.ebi.ac.uk/ipd/kir/align.html
			BLAST||https://www.ebi.ac.uk/ipd/kir/blast.html
			KIR Ligand Calculator||https://www.ebi.ac.uk/ipd/kir/ligand.html
			Cell Queries||https://www.ebi.ac.uk/ipd/kir/cell_query.html
		Removed:

Edits to 'https://fairsharing.org/FAIRsharing.h87prx' by 'The FAIRsharing Team' at 04:51, 08 Dec 2016 (approved):

	'contactName' has been modified:
		Before:
			
		After:
			Steven G. E. Marsh
		Added:
		Removed:

Support

General

FAQ	FAQ
contact form	IPD Contact Form
online documentation	KIR Haplotypes
online documentation	GitHub Repository
online documentation	Statistics
online documentation	KIR Nomenclature
online documentation	KIR Allele Nomenclature
online documentation	KIR Genotypes
online documentation	KIR Genes

Additional Information

Contact

Steven G. E. Marsh ORCID

Tools

KIR Alignment Tool	https://www.ebi.ac.uk/ipd/kir/align.html
BLAST	https://www.ebi.ac.uk/ipd/kir/blast.html
KIR Ligand Calculator	https://www.ebi.ac.uk/ipd/kir/ligand.html
Donor KIR B-content group calculator	https://www.ebi.ac.uk/ipd/kir/donor_b_content.html
IPD-KIR Allele Ethnicity Tool	https://www.ebi.ac.uk/ipd/kir/ethnicity.html

Access / Retrieve Data

Conditions of Use

Applies to: Data use

Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)

Data Release

Download

https://www.ebi.ac.uk/ipd/kir/download.html

Data Curation

Submit

https://www.ebi.ac.uk/ipd/kir/submit_stage_1.html

Data Access

Browse Fully Sequenced Haplotypes	https://www.ebi.ac.uk/ipd/kir/sequenced_haplotypes.html
Search Probes and Primers	https://www.ebi.ac.uk/ipd/kir/probe.html
Cell Queries	https://www.ebi.ac.uk/ipd/kir/cell_query.html

Publications

IPD--the Immuno Polymorphism Database.

Robinson J., Halliwell JA., McWilliam H., Lopez R., Marsh SG.,
Nucleic Acids Res. 2013

View Paper (PubMed) View Publication

IPD--the Immuno Polymorphism Database.

Robinson J,Mistry K,McWilliam H,Lopez R,Marsh SG
Nucleic Acids Res 2009

View Paper (PubMed) View Publication

Related Standards

Reporting Guidelines

No guidelines defined

Terminology Artifacts

No semantic standards defined

Models and Formats

No syntax standards defined

Identifier Schemas

No identifier schema standards defined

Metrics

No metrics standards defined

Related Databases

Implementing Policies

This record is not implemented by any policy.

Credit

Record Maintainer

This record is maintained by jamesran

Funds

National Institutes of Health (NIH), Bethesda, MD, USA (Government body)

Maintains

Anthony Nolan Research Institute, London, UK (Research institute)
Stanford University School of Medicine, CA, USA (University)
University of Minnesota (University)
European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, UK (Research institute)

Grant Number(s)

P01-CA-111412 (National Institutes of Health (NIH), Bethesda, MD, USA)

IPD-KIR - Killer-cell Immunoglobulin-like Receptors

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