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ready Minimum Information for Reporting Next Generation Sequencing Genotyping

Abbreviation: MIRING

General Information
MIRING defines the minimum information needed to describe genotyping results for HLA and KIR genes generated using Next Generation Sequencing (NGS) methods, allowing reinterpretation in light of continuous developments in reference sequence and genomic alignment resources for these genes. MIRING further defines the elements of a message to be used to exchange genotyping results. Use of MIRING ensures the long-term portability and broad application of NGS genotyping data for histocompatibility, immunogenetic and immunogenomic applications.


Countries that developed this resource United States

Created in 2014

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How to cite this record MIRING; Minimum Information for Reporting Next Generation Sequencing Genotyping; DOI:; Last edited: Jan. 8, 2019, 1:27 p.m.; Last accessed: Jan 29 2022 2:23 p.m.

This record is maintained by IDAWG  ORCID

Record added: Jan. 8, 2015, 11:53 p.m.
Record updated: April 12, 2017, 8:47 p.m. by IDAWG.

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Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing.

Mack SJ,Milius RP,Gifford BD,Sauter J,Hofmann J,Osoegawa K,Robinson J,Groeneweg M,Turenchalk GS,Adai A,Holcomb C,Rozemuller EH,Penning MT,Heuer ML,Wang C,Salit ML,Schmidt AH,Parham PR,Muller C,Hague T,Fischer G,Fernandez-Vina M,Hollenbach JA,Norman PJ,Maiers M
Hum Immunol 2015

View Paper (PubMed) View Publication

Histoimmunogenetics Markup Language 1.0: Reporting next generation sequencing-based HLA and KIR genotyping

Milius RP, Heuer M, Valiga D, Doroschak KJ, Kennedy CJ, Bolon YT, Schneider J, Pollack J, Kim HR, Cereb N, Hollenbach JA, Mack SJ, Maiers M
Human Immunology 2015

View Paper (PubMed) View Publication

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Grant Number(s)

  • N00014-08-1-1207 (Office of Naval Research, USA)

  • R01AI128775 (National Institute of Allergy and Infectious Diseases (NIAD), Bethesda, MD, USA)

  • R01GM109030 (U.S. National Library of Medicine)

  • U01AI067068 (U.S. National Library of Medicine)

  • U01AI090905 (U.S. National Library of Medicine)