VDJdb: a curated database of T-cell receptors with known antigen specificity
Abbreviation:VDJdb
General Information
The primary goal of VDJdb is to facilitate access to existing information on T-cell receptor antigen specificities, i.e. the ability to recognize certain epitopes in certain MHC contexts.
Our mission is to both aggregate the scarce TCR specificity information available so far and to create a curated repository to store such data.
In addition to routine database updates providing the most up-to-date information, we make our best to ensure data consistency and fight irregularities in TCR specificity reporting with a complex database validation scheme.
How to cite this record
FAIRsharing.org: VDJdb; VDJdb: a curated database of T-cell receptors with known antigen specificity; DOI: https://doi.org/10.25504/FAIRsharing.nwz68;
Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 26 2021 3:26 a.m.
Record added: Aug. 20, 2017, 7:01 p.m.
Record updated:
Aug. 21, 2017, 11:54 a.m. by The FAIRsharing Team.
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Edits to 'https://fairsharing.org/FAIRsharing.nwz68' by 'The FAIRsharing Team' at 11:54, 21 Aug 2017 (approved):
'description' has been modified:
Before: The primary goal of VDJdb is to facilitate access to existing information on T-cell receptor antigen specificities, i.e. the ability to recognize certain epitopes in certain MHC contexts. Our mission is to both aggregate the scarce TCR specificity information available so far and to create a curated repository to store such data. In addition to routine database updates providing the most up-to-date information|we make our best to ensure data consistency and fight irregularities in TCR specificity reporting with a complex database validation scheme: We take into account all available information on experimental setup used to identify antigen-specific TCR sequences and assign a single confidence score to highligh most reliable records at the database generation stage. Each database record is also automatically checked against a database of V/J segment germline sequences to ensure standardized and consistent reporting of V-J junctions and CDR3 sequences that define T-cell clones. Browser: https://vdjdb.cdr3.net Main repository: https://github.com/antigenomics/vdjdb-db Zenodo DOI: https://zenodo.org/record/838663
After: The primary goal of VDJdb is to facilitate access to existing information on T-cell receptor antigen specificities, i.e. the ability to recognize certain epitopes in certain MHC contexts. Our mission is to both aggregate the scarce TCR specificity information available so far and to create a curated repository to store such data. In addition to routine database updates providing the most up-to-date information|we make our best to ensure data consistency and fight irregularities in TCR specificity reporting with a complex database validation scheme. Domain list has changed: Previous values: Bioinformatics tools and formats||http://edamontology.org/topic_0091 Immunogenetics|None|http://purl.obolibrary.org/obo/OMIT_0008256 Immunogenomics|None| New values: Bioinformatics tools and formats||http://edamontology.org/topic_0091 Immunogenetics|None|http://purl.obolibrary.org/obo/OMIT_0008256 Immunogenomics|None| Medicine||http://edamontology.org/topic_3303 Biomedical Science|None|http://edamontology.org/topic_3344 Health sciences|None|http://www.fairsharing.org/fairsharing/FAIRO_0000095 Support links have changed: Previous values: https://github.com/antigenomics/vdjdb-db/issues New values: https://github.com/antigenomics/vdjdb-db/issues https://zenodo.org/record/838663#.WZq4IsaZOwI https://gitter.im/antigenomics/vdjdb-db Licenses have changed: Previous values: Creative Commons Attribution-NoDerivatives New values: Creative Commons Attribution-NoDerivs (CC BY-NC)
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