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Database of Interacting Proteins

Abbreviation:DIP

Recommended

General Information

The database of interacting protein (DIP) database stores experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions. The data stored within the DIP database were curated, both manually by expert curators and automatically using computational approaches that utilize the the knowledge about the protein-protein interaction networks extracted from the core DIP data.

Homepage https://dip.doe-mbi.ucla.edu

Countries that developed this resource United States

Created in 1999

Taxonomic range

All

Knowledge Domains

Subjects

In the following recommendations:

How to cite this record FAIRsharing.org: DIP; Database of Interacting Proteins; DOI: https://doi.org/10.25504/FAIRsharing.qje0v8; Last edited: June 23, 2021, 2 p.m.; Last accessed: Jul 31 2021 1:27 p.m.

Publication for citation The Database of Interacting Proteins: 2004 update. Salwinski L,Miller CS,Smith AJ,Pettit FK,Bowie JU,Eisenberg D; Nucleic Acids Res ; 2003; 10.1093/nar/gkh086;

Record updated: June 23, 2021, 1:58 p.m. by The FAIRsharing Team.

Show edit history

Edits to 'https://fairsharing.org/FAIRsharing.qje0v8' by 'The FAIRsharing Team' at 13:58, 23 Jun 2021 (approved):

	'onto_domains' has been modified:
		Before:
			Pathway or network prediction
			Protein interactions
			Protein-Protein Interaction
			protein
		After:
			Protein interactions
			Protein-Protein Interaction
			network model
			protein
		Added:
			network model
		Removed:
			Pathway or network prediction

Edits to 'https://fairsharing.org/FAIRsharing.qje0v8' by 'The FAIRsharing Team' at 13:17, 04 Mar 2021 (approved):

	'standardsImplemented' has been modified:
		Before:
			Molecular Interaction Tabular
			Mosquito Insecticide Resistance Ontology
			FASTA Sequence Format
			Common Metadata Elements for Cataloging Biomedical Datasets
		After:
			Molecular Interaction Tabular
			Mosquito Insecticide Resistance Ontology
			FASTA Sequence Format
			Common Metadata Elements for Cataloging Biomedical Datasets
			Molecular Interaction eXtensible Markup Language
			Minimum Information about a Molecular Interaction Experiment
		Added:
			Molecular Interaction eXtensible Markup Language
			Minimum Information about a Molecular Interaction Experiment
		Removed:

	'supportLinks' has been modified:
		Before:
			help|http://dip.doe-mbi.ucla.edu/dip/Guide.cgi
			online documentation|https://dip.doe-mbi.ucla.edu/dip/Stat.cgi
		After:
			help|https://dip.doe-mbi.ucla.edu/dip/Guide.cgi
			online documentation|https://dip.doe-mbi.ucla.edu/dip/Stat.cgi
			online documentation|https://dip.doe-mbi.ucla.edu/dip/Articles.cgi
		Added:
			help|https://dip.doe-mbi.ucla.edu/dip/Guide.cgi
			online documentation|https://dip.doe-mbi.ucla.edu/dip/Articles.cgi
		Removed:
			help|http://dip.doe-mbi.ucla.edu/dip/Guide.cgi

	'description' has been modified:
		Before: The database of interacting protein (DIP) database stores experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions
		After: The database of interacting protein (DIP) database stores experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions. The data stored within the DIP database were curated, both manually by expert curators and automatically using computational approaches that utilize the the knowledge about the protein-protein interaction networks extracted from the core DIP data.

	'licences' has been modified:
		Before:
			Creative Commons Attribution-NoDerivs 3.0 Unported (CC BY-ND 3.0)|https://creativecommons.org/licenses/by-nd/3.0/|Data
		After:
			Creative Commons Attribution-NoDerivs 3.0 Unported (CC BY-ND 3.0)|https://creativecommons.org/licenses/by-nd/3.0/|Data
			DIP Terms of Use|https://dip.doe-mbi.ucla.edu/dip/termsofuse.html|Data
		Added:
			DIP Terms of Use|https://dip.doe-mbi.ucla.edu/dip/termsofuse.html|Data
		Removed:

	'tools' has been modified:
		Before:
			Expression Profile Reliability (EPR) index||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=1
			The Paralogous Verification Method (PVM) Tool||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=2
			The Domain Pair Verification (DPV) Tool||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=3
		After:
		Added:
		Removed:
			Expression Profile Reliability (EPR) index||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=1
			The Paralogous Verification Method (PVM) Tool||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=2
			The Domain Pair Verification (DPV) Tool||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=3

	'onto_disciplines' has been modified:
		Before:
			Biology
			Life Science
		After:
			Biology
		Added:
		Removed:
			Life Science

	'onto_domains' has been modified:
		Before:
			Protein interactions
			protein
		After:
			Pathway or network prediction
			Protein interactions
			Protein-Protein Interaction
			protein
		Added:
			Pathway or network prediction
			Protein-Protein Interaction
		Removed:

	'dataProcesses' has been modified:
		Before:
			Download, data access, http://dip.doe-mbi.ucla.edu/dip/Download.cgi
			Submit Data, data curation, http://dip.doe-mbi.ucla.edu/dip/Submissions.cgi
			Search, data access, http://dip.doe-mbi.ucla.edu/dip/Search.cgi
		After:
			Download, data release, https://dip.doe-mbi.ucla.edu/dip/Download.cgi
			Submit Data, data curation, https://dip.doe-mbi.ucla.edu/dip/Submissions.cgi
			Search, data access, https://dip.doe-mbi.ucla.edu/dip/Search.cgi
			Expression Profile Reliability (EPR) index, data access, https://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=1
			The Paralogous Verification Method (PVM) Tool, data access, https://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=2
			The Domain Pair Verification (DPV) Tool, data access, https://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=3
		Added:
			Download, data release, https://dip.doe-mbi.ucla.edu/dip/Download.cgi
			Submit Data, data curation, https://dip.doe-mbi.ucla.edu/dip/Submissions.cgi
			Search, data access, https://dip.doe-mbi.ucla.edu/dip/Search.cgi
			Expression Profile Reliability (EPR) index, data access, https://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=1
			The Paralogous Verification Method (PVM) Tool, data access, https://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=2
			The Domain Pair Verification (DPV) Tool, data access, https://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=3
		Removed:
			Download, data access, http://dip.doe-mbi.ucla.edu/dip/Download.cgi
			Submit Data, data curation, http://dip.doe-mbi.ucla.edu/dip/Submissions.cgi
			Search, data access, http://dip.doe-mbi.ucla.edu/dip/Search.cgi

	'homepage' has been modified:
		Before: http://dip.doe-mbi.ucla.edu
		After: https://dip.doe-mbi.ucla.edu

Edits to 'https://fairsharing.org/FAIRsharing.qje0v8' by 'The FAIRsharing Team' at 11:49, 02 Jul 2019 (approved):

	'supportLinks' has been modified:
		Before:
			help|http://dip.doe-mbi.ucla.edu/dip/Guide.cgi
		After:
			help|http://dip.doe-mbi.ucla.edu/dip/Guide.cgi
			online documentation|https://dip.doe-mbi.ucla.edu/dip/Stat.cgi
		Added:
			online documentation|https://dip.doe-mbi.ucla.edu/dip/Stat.cgi
		Removed:

	'contact' has been modified:
		Before: None
		After: DIP General Contact

	'tools' has been modified:
		Before:
			The Domain Pair Verification (DPV) Tool||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=3
			submit||http://dip.doe-mbi.ucla.edu/dip/Submissions.cgi
			search||http://dip.doe-mbi.ucla.edu/dip/Search.cgi
			Expression Profile Reliability (EPR) index||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=1
			The Paralogous Verification Method (PVM) Tool||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=2
		After:
			The Domain Pair Verification (DPV) Tool||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=3
			Expression Profile Reliability (EPR) index||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=1
			The Paralogous Verification Method (PVM) Tool||http://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=2
		Added:
		Removed:
			submit||http://dip.doe-mbi.ucla.edu/dip/Submissions.cgi
			search||http://dip.doe-mbi.ucla.edu/dip/Search.cgi

	'onto_disciplines' has been modified:
		Before:
			Life Sciences
		After:
			Biology
			Life Sciences
		Added:
			Biology
		Removed:

	'dataProcesses' has been modified:
		Before:
			Download
		After:
			Download
			Submit Data
			Search
		Added:
			Submit Data
			Search
		Removed:

In Collections

NIH-supported data repositories

Data Citation Implementation

Open Science Prize

International Molecular Exchange Consortium (IMEx)

Support

General

help	User Guide
online documentation	Statistics
online documentation	DIP-related Publications

Additional Information

Contact

DIP General Contact

Tools

No tools defined

Access / Retrieve Data

Conditions of Use

Applies to: Data use

Data Release

Download

https://dip.doe-mbi.ucla.edu/dip/Download.cgi

Data Curation

Submit Data

https://dip.doe-mbi.ucla.edu/dip/Submissions.cgi

Data Access

Search	https://dip.doe-mbi.ucla.edu/dip/Search.cgi
Expression Profile Reliability (EPR) index	https://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=1
The Paralogous Verification Method (PVM) Tool	https://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=2
The Domain Pair Verification (DPV) Tool	https://dip.doe-mbi.ucla.edu/dip/Services.cgi?SM=3

Publications

DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions.

Xenarios I,Salwinski L,Duan XJ,Higney P,Kim SM,Eisenberg D
Nucleic Acids Res 2001

View Paper (PubMed)

The Database of Interacting Proteins: 2004 update.

Salwinski L,Miller CS,Smith AJ,Pettit FK,Bowie JU,Eisenberg D
Nucleic Acids Res 2003

View Paper (PubMed) View Publication

DIP: The Database of Interacting Proteins: 2001 update.

Xenarios I,Fernandez E,Salwinski L,Duan XJ,Thompson MJ,Marcotte EM,Eisenberg D
Nucleic Acids Res 2000

View Paper (PubMed)

DIP: the database of interacting proteins.

Xenarios I,Rice DW,Salwinski L,Baron MK,Marcotte EM,Eisenberg D
Nucleic Acids Res 1999

View Paper (PubMed)

Related Standards

Reporting Guidelines

Terminology Artifacts

Mosquito Insecticide Resistance Ontology

Models and Formats

Identifier Schemas

No identifier schema standards defined

Metrics

No metrics standards defined

Related Databases

Implementing Policies

Credit

Record Maintainer

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Maintains

University of California Los Angeles, USA (University) Lead

Database of Interacting Proteins

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