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ready Signaling Pathway Integrated Knowledge Engine


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SPIKE (Signaling Pathway Integrated Knowledge Engine) is an interactive software environment that graphically displays biological signaling networks, allows dynamic layout and navigation through these networks, and enables the superposition of DNA microarray and other functional genomics data on interaction maps.


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Created in 2007

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How to cite this record SPIKE; Signaling Pathway Integrated Knowledge Engine; DOI:; Last edited: April 26, 2021, 3:19 p.m.; Last accessed: Jan 24 2022 10:31 a.m.

Record updated: April 20, 2021, 11:40 a.m. by The FAIRsharing Team.

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SPIKE: a database of highly curated human signaling pathways.

Paz A., Brownstein Z., Ber Y., Bialik S., David E., Sagir D., Ulitsky I., Elkon R., Kimchi A., Avraham KB., Shiloh Y., Shamir R.,
Nucleic Acids Res. 2011

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