standards > terminology artifact > DOI:10.25504/FAIRsharing.spjjv8


ready Functional Therapeutic Chemical Classification System

Abbreviation: FTC


General Information
The Functional Therapeutic Chemical Classification System (FTC) defines over 20,000 mechanisms and modes of action for approved drugs. The resource abstracts away from the traditional chemical structure-based approach and focuses solely on the mode of action of drugs. The classification sorts therapeutic agents based on their function in the human body. Please note that this resource is no longer actively maintained (source: https://github.com/loopasam/ftc/issues/1).



How to cite this record FAIRsharing.org: FTC; Functional Therapeutic Chemical Classification System; DOI: https://doi.org/10.25504/FAIRsharing.spjjv8; Last edited: Feb. 12, 2020, 7:47 p.m.; Last accessed: Feb 23 2020 2:23 p.m.

Publication for citation  The functional therapeutic chemical classification system. Croset S,Overington JP,Rebholz-Schuhmann D; Bioinformatics ; 2013; 10.1093/bioinformatics/btt628;


Record added: Oct. 24, 2017, 9:41 a.m.
Record updated: Feb. 12, 2020, 7:47 p.m. by The FAIRsharing Team.

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The functional therapeutic chemical classification system.

Croset S,Overington JP,Rebholz-Schuhmann D
Bioinformatics 2013

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Implementing Databases (3)
ChEMBL
ChEMBL is an open large-scale bioactivity database containing information largely manually extracted from the medicinal chemistry literature. Information regarding the compounds tested (including their structures), the biological or physicochemical assays performed on these and the targets of these assays are recorded in a structured form, allowing users to address a broad range of drug discovery questions.

DrugBank
The DrugBank database is a freely available bioinformatics and chemoinformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.

UniProt Knowledgebase
The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation. In addition to capturing the core data mandatory for each UniProtKB entry (mainly, the amino acid sequence, protein name or description, taxonomic data and citation information), as much annotation information as possible is added. This includes widely accepted biological ontologies, classifications and cross-references, and clear indications of the quality of annotation in the form of evidence attribution of experimental and computational data. The UniProt Knowledgebase consists of two sections: a reviewed section containing manually-annotated records with information extracted from literature and curator-evaluated computational analysis (aka "UniProtKB/Swiss-Prot"), and an unreviewed section with computationally analyzed records that await full manual annotation (aka "UniProtKB/TrEMBL").

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