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Reactome - a curated knowledgebase of biological pathways

Abbreviation:Reactome

Recommended

General Information

The cornerstone of Reactome is a freely available, open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes, vaccines, anti-cancer therapeutics and small molecules) participating in reactions form a network of biological interactions and are grouped into pathways. Examples of biological pathways in Reactome include classical intermediary metabolism, signaling, transcriptional regulation, apoptosis and disease. Inferred orthologous reactions are available for 15 non-human species including mouse, rat, chicken, zebrafish, worm, fly, and yeast.

Homepage https://reactome.org

Countries that developed this resource Canada , United Kingdom , United States

Created in 2004

Taxonomic range

Bos taurus

Caenorhabditis elegans

Canis familiaris

Danio rerio

Dictyostelium discoideum

Drosophila melanogaster

Gallus gallus

Homo sapiens

Mus musculus

Mycobacterium tuberculosis

Plasmodium falciparum

Rattus norvegicus

Saccharomyces cerevisiae

Schizosaccharomyces pombe

Sus scrofa

Xenopus tropicalis

Knowledge Domains

Subjects

User-defined Tags

COVID-19

In the following recommendations:

How to cite this record FAIRsharing.org: Reactome; Reactome - a curated knowledgebase of biological pathways; DOI: https://doi.org/10.25504/FAIRsharing.tf6kj8; Last edited: March 12, 2021, 10:46 a.m.; Last accessed: Oct 19 2021 2:16 p.m.

Publication for citation The reactome pathway knowledgebase. Jassal B,Matthews L,Viteri G,Gong C,Lorente P,Fabregat A,Sidiropoulos K,Cook J,Gillespie M,Haw R,Loney F,May B,Milacic M,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P; Nucleic Acids Res ; 2019; 10.1093/nar/gkz1031;

This record is maintained by reactome

Record updated: March 11, 2021, 4:48 p.m. by The FAIRsharing Team.

Show edit history

Edits to 'https://fairsharing.org/FAIRsharing.tf6kj8' by 'The FAIRsharing Team' at 16:48, 11 Mar 2021 (approved):

	'standardsImplemented' has been modified:
		Before:
			Biological Pathway eXchange
			Chemical Entities of Biological Interest
			Systems Biology Graphical Notation
			Molecular Interaction Tabular
			Gene Ontology
			Systems Biology Markup Language
			Schema.org
			PRotein Ontology
			Human Interaction Network Ontology
			Gene Ontology (GO) Gene Association File Format 2.0
			Gene Ontology (GO) Gene Association File Format 2.1
			Gene Ontology (GO) Gene Association File Format 2.2
		After:
			Biological Pathway eXchange
			Chemical Entities of Biological Interest
			Systems Biology Graphical Notation
			Molecular Interaction Tabular
			Gene Ontology
			Systems Biology Markup Language
			Schema.org
			PRotein Ontology
			Human Interaction Network Ontology
			Bioschemas
			Digital Object Identifier
			Gene Ontology (GO) Gene Association File Format 2.0
			Gene Ontology (GO) Gene Association File Format 2.1
			Gene Ontology (GO) Gene Association File Format 2.2
		Added:
			Bioschemas
			Digital Object Identifier
		Removed:

	'licences' has been modified:
		Before:
			Creative Commons CC0 1.0 Universal (CC0 1.0) Public Domain Dedication|https://creativecommons.org/publicdomain/zero/1.0/|Data
			Creative Commons Attribution 4.0 International (CC BY 4.0)|https://creativecommons.org/licenses/by/4.0/|Software
		After:
			Creative Commons CC0 1.0 Universal (CC0 1.0) Public Domain Dedication|https://creativecommons.org/publicdomain/zero/1.0/|Data
			Creative Commons Attribution 4.0 International (CC BY 4.0)|https://creativecommons.org/licenses/by/4.0/|Software
			Reactome Licence Agreement|https://reactome.org/license|Data
		Added:
			Reactome Licence Agreement|https://reactome.org/license|Data
		Removed:

	'dataProcesses' has been modified:
		Before:
			Download, data access, https://reactome.org/download-data
			Browse, data access, http://www.reactome.org/PathwayBrowser/
			Advanced Search, data access, https://www.reactome.org/content/advanced
			Browse DOIs, data access, https://reactome.org/cgi-bin/doi_toc?DB=current
		After:
			Download, data access, https://reactome.org/download-data
			Browse, data access, https://www.reactome.org/PathwayBrowser/
			Advanced Search, data access, https://www.reactome.org/content/advanced
			Browse DOIs, data access, https://reactome.org/cgi-bin/doi_toc?DB=current
			Analyze with the Pathway Browser, data access, http://www.reactome.org/PathwayBrowser/#TOOL=AT
		Added:
			Browse, data access, https://www.reactome.org/PathwayBrowser/
			Analyze with the Pathway Browser, data access, http://www.reactome.org/PathwayBrowser/#TOOL=AT
		Removed:
			Browse, data access, http://www.reactome.org/PathwayBrowser/

	'publications' has been modified:
		Before:
			Reactome: a knowledgebase of biological pathways.|Joshi-Tope G., Gillespie M., Vastrik I., D'Eustachio P., Schmidt E., de Bono B., Jassal B., Gopinath GR., Wu GR., Matthews L., Lewis S., Birney E., Stein L., |Nucleic Acids Res.|2005
			The Reactome Pathway Knowledgebase.|Fabregat A,Jupe S,Matthews L,Sidiropoulos K,Gillespie M,Garapati P,Haw R,Jassal B,Korninger F,May B,Milacic M,Roca CD,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Viteri G,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P|Nucleic Acids Res|2017
		After:
			Reactome: a knowledgebase of biological pathways.|Joshi-Tope G., Gillespie M., Vastrik I., D'Eustachio P., Schmidt E., de Bono B., Jassal B., Gopinath GR., Wu GR., Matthews L., Lewis S., Birney E., Stein L., |Nucleic Acids Res.|2005
			The Reactome Pathway Knowledgebase.|Fabregat A,Jupe S,Matthews L,Sidiropoulos K,Gillespie M,Garapati P,Haw R,Jassal B,Korninger F,May B,Milacic M,Roca CD,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Viteri G,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P|Nucleic Acids Res|2017
			The reactome pathway knowledgebase.|Jassal B,Matthews L,Viteri G,Gong C,Lorente P,Fabregat A,Sidiropoulos K,Cook J,Gillespie M,Haw R,Loney F,May B,Milacic M,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P|Nucleic Acids Res|2019
		Added:
			The reactome pathway knowledgebase.|Jassal B,Matthews L,Viteri G,Gong C,Lorente P,Fabregat A,Sidiropoulos K,Cook J,Gillespie M,Haw R,Loney F,May B,Milacic M,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P|Nucleic Acids Res|2019
		Removed:

	'accessPoints' has been modified:
		Before:
			REST|http://reactome.org/AnalysisService/|Pathway Analysis Service API
			REST|https://reactome.org/ContentService/|Content Service API
		After:
			REST|https://reactome.org/AnalysisService/|Pathway Analysis Service API
			REST|https://reactome.org/ContentService/|Content Service API
		Added:
			REST|https://reactome.org/AnalysisService/|Pathway Analysis Service API
		Removed:
			REST|http://reactome.org/AnalysisService/|Pathway Analysis Service API

	'tools' has been modified:
		Before:
			Analyze with the Pathway Browser||http://www.reactome.org/PathwayBrowser/#TOOL=AT
			ReactomeFIVIz||https://reactome.org/tools/reactome-fiviz
		After:
			ReactomeFIVIz||https://reactome.org/tools/reactome-fiviz
		Added:
		Removed:
			Analyze with the Pathway Browser||http://www.reactome.org/PathwayBrowser/#TOOL=AT

Edits to 'https://fairsharing.org/FAIRsharing.tf6kj8' by 'reactome' at 17:37, 24 Jun 2020 (approved):

'description' has been modified:
Before: The cornerstone of Reactome is a freely available, open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes, vaccines, anti-cancer therapeutics and small molecules) participating in reactions form a network of biological interactions and are grouped into pathways. Examples of biological pathways in Reactome include classical intermediary metabolism, signaling, transcriptional regulation, apoptosis and disease. Inferred orthologous reactions are available for 15 non-human species including mouse, rat, chicken, puffer fish, worm, fly, and yeast.

After: The cornerstone of Reactome is a freely available, open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes, vaccines, anti-cancer therapeutics and small molecules) participating in reactions form a network of biological interactions and are grouped into pathways. Examples of biological pathways in Reactome include classical intermediary metabolism, signaling, transcriptional regulation, apoptosis and disease. Inferred orthologous reactions are available for 15 non-human species including mouse, rat, chicken, zebrafish, worm, fly, and yeast.

Edits to 'https://fairsharing.org/FAIRsharing.tf6kj8' by 'reactome' at 16:34, 24 Jun 2020 (approved):

	'yearOfCreation' has been modified:
		Before: 2002
		After: 2004

Edits to 'https://fairsharing.org/FAIRsharing.tf6kj8' by 'reactome' at 16:32, 24 Jun 2020 (approved):

	'yearOfCreation' has been modified:
		Before: 2003
		After: 2002

	'taxonomies' has been modified:
		Before:
			All
		After:
			Bos taurus
			Caenorhabditis elegans
			Canis familiaris
			Danio rerio
			Dictyostelium discoideum
			Drosophila melanogaster
			Gallus gallus
			Homo sapiens
			Mus musculus
			Mycobacterium tuberculosis
			Plasmodium falciparum
			Rattus norvegicus
			Saccharomyces cerevisiae
			Schizosaccharomyces pombe
			Sus scrofa
			Xenopus tropicalis
		Added:
			Bos taurus
			Caenorhabditis elegans
			Canis familiaris
			Danio rerio
			Dictyostelium discoideum
			Drosophila melanogaster
			Gallus gallus
			Homo sapiens
			Mus musculus
			Mycobacterium tuberculosis
			Plasmodium falciparum
			Rattus norvegicus
			Saccharomyces cerevisiae
			Schizosaccharomyces pombe
			Sus scrofa
			Xenopus tropicalis
		Removed:
			All

	'homepage' has been modified:
		Before: http://www.reactome.org
		After: https://reactome.org

	'description' has been modified:
		Before: The cornerstone of Reactome is a freely available, open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes, vaccines, anti-cancer therapeutics and small molecules) participating in reactions form a network of biological interactions and are grouped into pathways. Examples of biological pathways in Reactome include classical intermediary metabolism, signaling, transcriptional regulation, apoptosis and disease. Inferred orthologous reactions are available for 17 non-human species including mouse, rat, chicken, puffer fish, worm, fly, yeast, rice, and Arabidopsis.


		After: The cornerstone of Reactome is a freely available, open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes, vaccines, anti-cancer therapeutics and small molecules) participating in reactions form a network of biological interactions and are grouped into pathways. Examples of biological pathways in Reactome include classical intermediary metabolism, signaling, transcriptional regulation, apoptosis and disease. Inferred orthologous reactions are available for 15 non-human species including mouse, rat, chicken, puffer fish, worm, fly, and yeast.

Edits to 'https://fairsharing.org/FAIRsharing.tf6kj8' by 'The FAIRsharing Team' at 14:38, 21 Apr 2020 (approved):

	'user_defined_tags' has been modified:
		Before:
		After:
			COVID-19
		Added:
			COVID-19
		Removed:

	'onto_disciplines' has been modified:
		Before:
			Life Science
		After:
			Epidemiology
			Life Science
			Virology
		Added:
			Epidemiology
			Virology
		Removed:

	'supportLinks' has been modified:
		Before:
			online documentation|https://reactome.org/documentation
			online documentation|https://reactome.org/content/schema/DatabaseObject
			online documentation|https://reactome.org/documentation/inferred-events
			tess training|https://tess.elixir-europe.org/materials/pathway-visualization-in-the-reactome-pathway-database
			tess training|https://tess.elixir-europe.org/materials/reactome
			training|https://reactome.org/community/training
			twitter|@reactome
		After:
			TeSS training|https://tess.elixir-europe.org/materials/pathway-visualization-in-the-reactome-pathway-database
			TeSS training|https://tess.elixir-europe.org/materials/reactome
			online documentation|https://reactome.org/documentation/inferred-events
			online documentation|https://reactome.org/documentation
			online documentation|https://reactome.org/content/schema/DatabaseObject
			training|https://reactome.org/community/training
			twitter|@reactome
		Added:
			TeSS training|https://tess.elixir-europe.org/materials/pathway-visualization-in-the-reactome-pathway-database
			TeSS training|https://tess.elixir-europe.org/materials/reactome
		Removed:
			tess training|https://tess.elixir-europe.org/materials/pathway-visualization-in-the-reactome-pathway-database
			tess training|https://tess.elixir-europe.org/materials/reactome

Edits to 'https://fairsharing.org/FAIRsharing.tf6kj8' by 'The FAIRsharing Team' at 13:07, 10 Jan 2019 (approved):

	'organizations' has been modified:
		Before:
			Swiss Institute of Bioinformatics (SIB), Switzerland|https://www.sib.swiss|Maintains
		After:
			New York University Langone Medical Center (NYULMC), New York, USA|https://nyulangone.org/|Maintains
			Ontario Institute For Cancer Research, Toronto, ON, Canada|http://oicr.on.ca/|Maintains
			European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, UK|https://www.ebi.ac.uk/|Maintains
			Oregon Health & Science University, USA|http://www.ohsu.edu/xd/education/library/about/departments/ontology-development.cfm|Maintains
		Added:
			New York University Langone Medical Center (NYULMC), New York, USA|https://nyulangone.org/|Maintains
			Ontario Institute For Cancer Research, Toronto, ON, Canada|http://oicr.on.ca/|Maintains
			European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, UK|https://www.ebi.ac.uk/|Maintains
			Oregon Health & Science University, USA|http://www.ohsu.edu/xd/education/library/about/departments/ontology-development.cfm|Maintains
		Removed:
			Swiss Institute of Bioinformatics (SIB), Switzerland|https://www.sib.swiss|Maintains

	'supportLinks' has been modified:
		Before:
			online documentation|http://wiki.reactome.org/index.php/Usersguide
			twitter|@reactome
		After:
			online documentation|https://reactome.org/documentation
			online documentation|https://reactome.org/content/schema/DatabaseObject
			online documentation|https://reactome.org/documentation/inferred-events
			tess training|https://tess.elixir-europe.org/materials/pathway-visualization-in-the-reactome-pathway-database
			tess training|https://tess.elixir-europe.org/materials/reactome
			training|https://reactome.org/community/training
			twitter|@reactome
		Added:
			online documentation|https://reactome.org/documentation
			online documentation|https://reactome.org/content/schema/DatabaseObject
			online documentation|https://reactome.org/documentation/inferred-events
			tess training|https://tess.elixir-europe.org/materials/pathway-visualization-in-the-reactome-pathway-database
			tess training|https://tess.elixir-europe.org/materials/reactome
			training|https://reactome.org/community/training
		Removed:
			online documentation|http://wiki.reactome.org/index.php/Usersguide

	'description' has been modified:
		Before: The Reactome project is a collaboration to develop a curated resource of core pathways and reactions in human biology.
		After: The cornerstone of Reactome is a freely available, open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes, vaccines, anti-cancer therapeutics and small molecules) participating in reactions form a network of biological interactions and are grouped into pathways. Examples of biological pathways in Reactome include classical intermediary metabolism, signaling, transcriptional regulation, apoptosis and disease. Inferred orthologous reactions are available for 17 non-human species including mouse, rat, chicken, puffer fish, worm, fly, yeast, rice, and Arabidopsis.



	'licences' has been modified:
		Before:
			Open Data Commons (ODC) Public Domain Dedication and Licence (PDDL) 1.0|http://opendatacommons.org/licenses/pddl/1.0/|Data
		After:
			Creative Commons CC0 1.0 Universal (CC0 1.0) Public Domain Dedication|https://creativecommons.org/publicdomain/zero/1.0/|Data
			Creative Commons Attribution 4.0 International (CC BY 4.0)|https://creativecommons.org/licenses/by/4.0/|Software
		Added:
			Creative Commons CC0 1.0 Universal (CC0 1.0) Public Domain Dedication|https://creativecommons.org/publicdomain/zero/1.0/|Data
			Creative Commons Attribution 4.0 International (CC BY 4.0)|https://creativecommons.org/licenses/by/4.0/|Software
		Removed:
			Open Data Commons (ODC) Public Domain Dedication and Licence (PDDL) 1.0|http://opendatacommons.org/licenses/pddl/1.0/|Data

	'yearOfCreation' has been modified:
		Before: 2004
		After: 2003

	'onto_domains' has been modified:
		Before:
			Reaction data
			curated information
			pathway
		After:
			Drug Interaction
			Protein interactions
			Reaction data
			biological regulation
			curated information
			disease
			genetic interaction
			molecular interaction
			pathway
			signaling
		Added:
			Drug Interaction
			Protein interactions
			biological regulation
			disease
			genetic interaction
			molecular interaction
			signaling
		Removed:

	'dataProcesses' has been modified:
		Before:
			Download
			browse
			search
		After:
			Download
			Browse
			Advanced Search
			Browse DOIs
		Added:
			Browse
			Advanced Search
			Browse DOIs
		Removed:
			browse
			search

	'publications' has been modified:
		Before:
			Reactome: a knowledgebase of biological pathways.|Joshi-Tope G., Gillespie M., Vastrik I., D'Eustachio P., Schmidt E., de Bono B., Jassal B., Gopinath GR., Wu GR., Matthews L., Lewis S., Birney E., Stein L., |Nucleic Acids Res.|2005
		After:
			Reactome: a knowledgebase of biological pathways.|Joshi-Tope G., Gillespie M., Vastrik I., D'Eustachio P., Schmidt E., de Bono B., Jassal B., Gopinath GR., Wu GR., Matthews L., Lewis S., Birney E., Stein L., |Nucleic Acids Res.|2005
			The Reactome Pathway Knowledgebase.|Fabregat A,Jupe S,Matthews L,Sidiropoulos K,Gillespie M,Garapati P,Haw R,Jassal B,Korninger F,May B,Milacic M,Roca CD,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Viteri G,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P|Nucleic Acids Res|2017
		Added:
			The Reactome Pathway Knowledgebase.|Fabregat A,Jupe S,Matthews L,Sidiropoulos K,Gillespie M,Garapati P,Haw R,Jassal B,Korninger F,May B,Milacic M,Roca CD,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Viteri G,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P|Nucleic Acids Res|2017
		Removed:

	'accessPoints' has been modified:
		Before:
		After:
			REST|http://reactome.org/AnalysisService/|Pathway Analysis Service API
			REST|https://reactome.org/ContentService/|Content Service API
		Added:
			REST|http://reactome.org/AnalysisService/|Pathway Analysis Service API
			REST|https://reactome.org/ContentService/|Content Service API
		Removed:

	'tools' has been modified:
		Before:
			analyze||http://www.reactome.org/PathwayBrowser/#TOOL=AT
			Pathway Analysis Service API||http://reactome.org/AnalysisService/
		After:
			Analyze with the Pathway Browser||http://www.reactome.org/PathwayBrowser/#TOOL=AT
			ReactomeFIVIz||https://reactome.org/tools/reactome-fiviz
		Added:
			Analyze with the Pathway Browser||http://www.reactome.org/PathwayBrowser/#TOOL=AT
			ReactomeFIVIz||https://reactome.org/tools/reactome-fiviz
		Removed:
			analyze||http://www.reactome.org/PathwayBrowser/#TOOL=AT
			Pathway Analysis Service API||http://reactome.org/AnalysisService/

Edits to 'https://fairsharing.org/FAIRsharing.tf6kj8' by 'The FAIRsharing Team' at 19:39, 03 Feb 2018 (approved):

	'related_standards' has been modified:
		Before:
			bsg-s000038|Biological Pathway eXchange
			bsg-s000052|Systems Biology Markup Language
			bsg-s000092|Systems Biology Graphical Notation
			bsg-s000039|Chemical Entities of Biological Interest
			bsg-s000120|Molecular Interaction Tabular
			bsg-s000089|Gene Ontology
		After:
			bsg-s000038|Biological Pathway eXchange
			bsg-s000052|Systems Biology Markup Language
			bsg-s000092|Systems Biology Graphical Notation
			bsg-s000039|Chemical Entities of Biological Interest
			bsg-s000120|Molecular Interaction Tabular
			bsg-s000089|Gene Ontology
			bsg-s000593|Schema.org
		Added:
			bsg-s000593|Schema.org
		Removed:

Edits to 'https://fairsharing.org/FAIRsharing.tf6kj8' by 'reactome' at 03:31, 21 Mar 2017 (approved):

	'contactName' has been modified:
		Before:
			
		After:
			Reactome Helpdesk
			Countries have changed: 
			Previous values:
			European Union
			United States of America
			New values: 
			Canada
			United States of America
			United Kingdom
			Related standards have changed: 
			Previous values:
			bsg-s000039:Chemical Entities of Biological Interest
			bsg-s000089:Gene Ontology
			bsg-s000120:Molecular Interaction Tabular
			bsg-s000052:Systems Biology Markup Language
			New values: 
			bsg-s000039:Chemical Entities of Biological Interest
			bsg-s000089:Gene Ontology
			bsg-s000038:Biological Pathway eXchange
			bsg-s000120:Molecular Interaction Tabular
			bsg-s000052:Systems Biology Markup Language
			bsg-s000092:Systems Biology Graphical Notation
			Related databases have changed: 
			Previous values:
			biodbcore-000095: Rhea
			biodbcore-000155: WikiPathways
			biodbcore-000230: BindingDB database of measured binding affinities
			biodbcore-000420: Pathway Commons
			biodbcore-000495: Biological General Repository for Interaction Datasets
			biodbcore-000541: Type 1 Diabetes Database
			biodbcore-000755: MetaNetX
			biodbcore-000848: Open Targets
			New values: 
			biodbcore-000095: Rhea
			biodbcore-000155: WikiPathways
			biodbcore-000420: Pathway Commons
			biodbcore-000755: MetaNetX
			biodbcore-000848: Open Targets
			biodbcore-000663: Kyoto Encyclopedia of Genes and Genomes
			biodbcore-000523: Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins
			biodbcore-000054: IntAct molecular interaction database
		Added:
		Removed:

In Collections

RDA Covid-19 WG Resources

Support

General

online documentation	Reactome User Guide
online documentation	Data Schema
online documentation	Computationally-inferred Events
training	Reactome Training Material
twitter	@reactome

Additional Information

Contact

Reactome Helpdesk

TeSS training resources

Pathway visualization in the Reactome pathway database

Reactome

Tools

ReactomeFIVIz

https://reactome.org/tools/reactome-fiviz

Access / Retrieve Data

Conditions of Use

Applies to: Data use

Applies to: Database software

Creative Commons Attribution 4.0 International (CC BY 4.0)

Data Access

Download	https://reactome.org/download-data
Browse	https://www.reactome.org/PathwayBrowser/
Advanced Search	https://www.reactome.org/content/advanced
Browse DOIs	https://reactome.org/cgi-bin/doi_toc?DB=current
Analyze with the Pathway Browser	http://www.reactome.org/PathwayBrowser/#TOOL=AT

REST Web Services

Pathway Analysis Service API	https://reactome.org/AnalysisService/
Content Service API	https://reactome.org/ContentService/

Publications

Reactome: a knowledgebase of biological pathways.

Joshi-Tope G., Gillespie M., Vastrik I., D'Eustachio P., Schmidt E., de Bono B., Jassal B., Gopinath GR., Wu GR., Matthews L., Lewis S., Birney E., Stein L.,
Nucleic Acids Res. 2005

View Paper (PubMed) View Publication

The Reactome Pathway Knowledgebase.

Fabregat A,Jupe S,Matthews L,Sidiropoulos K,Gillespie M,Garapati P,Haw R,Jassal B,Korninger F,May B,Milacic M,Roca CD,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Viteri G,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P
Nucleic Acids Res 2017

View Paper (PubMed) View Publication

The reactome pathway knowledgebase.

Jassal B,Matthews L,Viteri G,Gong C,Lorente P,Fabregat A,Sidiropoulos K,Cook J,Gillespie M,Haw R,Loney F,May B,Milacic M,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P
Nucleic Acids Res 2019

View Paper (PubMed) View Publication

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New York University Langone Medical Center (NYULMC), New York, USA (Research institute)
Ontario Institute For Cancer Research (OICR), Toronto, ON, Canada (Research institute)
European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, UK (Research institute)
Oregon Health & Science University (OHSU), USA (University)

Reactome - a curated knowledgebase of biological pathways

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