bNAber
General Information
Discovery of Broadly Neutralizing Antibodies (bNAbs) has given a great boost to HIV vaccine research. Study of bNAbs capable of neutralizing a broad array of different HIV strains is important for a number of reasons: (i) structures of antigens co-crystallized with bNAbs are used as templates in HIV vaccine design; (ii) bNAbs can be effective as therapeutics; (iii) preventive use of bNAbs is a promising direction in AIDS care. The goal of bNAber is to collect, analyze, compare and present bNAbs data, thus helping researchers to create HIV vaccine.
How to cite this record
FAIRsharing.org: bNAber; bNAber; DOI: https://doi.org/10.25504/FAIRsharing.tgjsm4;
Last edited: June 3, 2019, 11:23 a.m.; Last accessed: Mar 05 2021 11:25 p.m.
Publication for citation
bNAber: database of broadly neutralizing HIV antibodies
Alexey Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton and Adam Godzik; NAR Database Issue ;
2014.
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Edits to 'https://fairsharing.org/FAIRsharing.tgjsm4' by 'The FAIRsharing Team' at 11:23, 03 Jun 2019 (approved):
'supportLinks' has been modified:
Before:
email|support@bnaber.org
help|http://www.bnaber.org/?q=Help
training|http://bnaber.org/?q=Use%20Cases
After:
help|http://bnaber.org/?q=Help
online documentation|http://bnaber.org/?q=node/12
online documentation|http://bnaber.org/?q=node/153
training|http://bnaber.org/?q=Use%20Cases
training|http://bnaber.org/?q=Walkthrough%20Videos
Added:
help|http://bnaber.org/?q=Help
online documentation|http://bnaber.org/?q=node/12
online documentation|http://bnaber.org/?q=node/153
training|http://bnaber.org/?q=Walkthrough%20Videos
Removed:
email|support@bnaber.org
help|http://www.bnaber.org/?q=Help
'description' has been modified:
Before: The discovery of broadly neutralizing antibodies (bNAbs) has provided an enormous impetus to
the HIV vaccine research and to entire immunology. The bNAber database
provides open, user friendly access to detailed data on the rapidly growing
list of HIV bNAbs, including neutralization profiles, sequences, and three-dimensional structures
(when available). It also provides an extensive list of visualization and analysis tools, such as
heatmaps to analyze neutralization data as well as structure and sequence viewers to correlate
bNAbs properties with structural and sequence features of individual antibodies. The goal of the
bNAber database is to enable researchers in this field to easily compare and analyze available
information on bNAbs thereby supporting efforts to design an effective vaccine for HIV/AIDS. The
bNAber database not only provides easy access to data that currently is scattered in the
supplementary materials sections of individual papers, but also contributes to the development
of general standards of data that have to be presented with the discovery of new bNAbs
and a universal mechanism of how such data can be shared.
After: Discovery of Broadly Neutralizing Antibodies (bNAbs) has given a great boost to HIV vaccine research. Study of bNAbs capable of neutralizing a broad array of different HIV strains is important for a number of reasons: (i) structures of antigens co-crystallized with bNAbs are used as templates in HIV vaccine design; (ii) bNAbs can be effective as therapeutics; (iii) preventive use of bNAbs is a promising direction in AIDS care. The goal of bNAber is to collect, analyze, compare and present bNAbs data, thus helping researchers to create HIV vaccine.
'tools' has been modified:
Before:
Jmol: an open-source Java viewer for chemical structures in 3D|13|http://jmol.sourceforge.net/
MView|1.56|http://www.ebi.ac.uk/Tools/msa/mview/
Partial Order Structure Alignment|2|http://fatcat.burnham.org/POSA/
After:
Analysis Tools||http://bnaber.org/?q=node/115
Structure Alignment||http://bnaber.org/?q=Structure%20Alignment%20Matrix
Neutralization Workbench||http://bnaber.org/?q=NeutSandbox
Added:
Analysis Tools||http://bnaber.org/?q=node/115
Structure Alignment||http://bnaber.org/?q=Structure%20Alignment%20Matrix
Neutralization Workbench||http://bnaber.org/?q=NeutSandbox
Removed:
Jmol: an open-source Java viewer for chemical structures in 3D|13|http://jmol.sourceforge.net/
MView|1.56|http://www.ebi.ac.uk/Tools/msa/mview/
Partial Order Structure Alignment|2|http://fatcat.burnham.org/POSA/
'onto_disciplines' has been modified:
Before:
Biomedical Science
After:
Biomedical Science
Immunogenetics
Immunology
Added:
Immunogenetics
Immunology
Removed:
'dataProcesses' has been modified:
Before:
manual curation
User Data Submission
Database Export (SQL)
submit
After:
manual curation
User Data Submission
Database Export (SQL)
Browse Solved Structures
Added:
Browse Solved Structures
Removed:
submit
'contactEmail' has been modified:
Before: aleblanc@sanfordburnham.org
After: support@bnaber.org
'contact' has been modified:
Before: Andrew LeBlanc
After: bNAber Support
'miriam_id' has been modified:
Before: None
After:
'homepage' has been modified:
Before: http://www.bnaber.org
After: http://bnaber.org/
Edits to 'https://fairsharing.org/FAIRsharing.tgjsm4' by 'The FAIRsharing Team' at 02:01, 14 Dec 2016 (approved):
'name' has been modified:
Before: bNAber: broadly Neutralizing Antibody electronic resource
After: bNAber
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Publications
bNAber: database of broadly neutralizing HIV antibodies
Alexey Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton and Adam Godzik
NAR Database Issue 2014
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