Drug Target Ontology
How to cite this record FAIRsharing.org: DTO; Drug Target Ontology; DOI: https://doi.org/10.25504/FAIRsharing.tke3y2; Last edited: June 21, 2018, 1:49 p.m.; Last accessed: Nov 19 2018 5:45 p.m.
Record added: Oct. 24, 2017, 9:41 a.m.
Record updated: June 21, 2018, 1:49 p.m. by The FAIRsharing Team.
Edits to 'https://fairsharing.org/FAIRsharing.tke3y2' by 'The FAIRsharing Team' at 11:28, 16 Jan 2018 (approved): 'organizations' has been modified: Before: NIH Common Fund|Government body|Funds Center for Computational Science (CCS)|University of Miami|Miami|FL|USA|University|Maintains NIH Common Fund|USA|Government body|Funds After: NIH Common Fund|USA|Government body|Funds Center for Computational Science (CCS)|University of Miami|Miami|FL|USA|University|Maintains Added: Removed: NIH Common Fund|Government body|Funds
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No XSD schemas defined
Conditions of UseApplies to: Data use
Drug target ontology to classify and integrate drug discovery data.
Lin Y,Mehta S,Kucuk-McGinty H,Turner JP,Vidovic D,Forlin M,Koleti A,Nguyen DT,Jensen LJ,Guha R,Mathias SL,Ursu O,Stathias V,Duan J,Nabizadeh N,Chung C,Mader C,Visser U,Yang JJ,Bologa CG,Oprea TI,Schurer SC
J Biomed Semantics 2017
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No guidelines defined
No semantic standards defined
Models and Formats
No identifier schema standards defined
TCRD is the central resource behind the Illuminating the Druggable Genome Knowledge Management Center (IDG-KMC). TCRD contains information about human targets, with special emphasis on four families of targets that are central to the NIH IDG initiative: GPCRs, kinases, ion channels and nuclear receptors. Olfactory GPCRs (oGPCRs) are treated as a separate family. A key aim of the KMC is to classify the development/druggability level of targets. The official public portal for TCRD is Pharos (pharos.nih.gov). Based on modern web design principles the Pharos interface provides facile access to all data types collected by the KMC. Given the complexity of the data surrounding any target, efficient and intuitive visualization has been a high priority, to enable users to quickly navigate & summarize search results and rapidly identify patterns. A critical feature of the interface is the ability to perform flexible search and subsequent drill down of search results. Underlying the interface is a RESTful API that provides programmatic access to all KMC data, allowing for easy consumption in user applications.
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NIH Common Fund, USA (Government body)
U54CA189205 (Illuminating the Druggable Genome Knowledge Management Center, Tudor Oprea, PI) (NIH Common Fund, USA)