Drug Target Ontology
Abbreviation: DTO
Homepage http://drugtargetontology.org/
Countries that developed this resource United States
Created in 2015
Taxonomic range
Knowledge Domains
Subjects
User-defined Tags
How to cite this record FAIRsharing.org: DTO; Drug Target Ontology; DOI: https://doi.org/10.25504/FAIRsharing.tke3y2; Last edited: Jan. 8, 2019, 1:40 p.m.; Last accessed: Jan 20 2021 4:19 p.m.
Record added: Oct. 24, 2017, 9:41 a.m.
Record updated:
June 21, 2018, 1:49 p.m. by The FAIRsharing Team.
contact form | Contact Form |
online documentation | Introcuction to DTO in Pharos |
online documentation | GitHub repository |
Additional Information
Contact | Stephan Schurer |
External Links
Bioportal | http://bioportal.bioontology.org/ontologies/DTO |
No XSD schemas defined
Drug target ontology to classify and integrate drug discovery data.
Lin Y,Mehta S,Kucuk-McGinty H,Turner JP,Vidovic D,Forlin M,Koleti A,Nguyen DT,Jensen LJ,Guha R,Mathias SL,Ursu O,Stathias V,Duan J,Nabizadeh N,Chung C,Mader C,Visser U,Yang JJ,Bologa CG,Oprea TI,Schurer SC
J Biomed Semantics 2017
View in BioPortal.
Reporting Guidelines
No guidelines defined
Terminology Artifacts
No semantic standards defined
Models and Formats
Identifier Schemas
No identifier schema standards defined
Metrics
No metrics standards defined
TCRD is the central resource behind the Illuminating the Druggable Genome Knowledge Management Center (IDG-KMC). TCRD contains information about human targets, with special emphasis on four families of targets that are central to the NIH IDG initiative: GPCRs, kinases, ion channels and nuclear receptors. Olfactory GPCRs (oGPCRs) are treated as a separate family. A key aim of the KMC is to classify the development/druggability level of targets. The official public portal for TCRD is Pharos (pharos.nih.gov). Based on modern web design principles the Pharos interface provides facile access to all data types collected by the KMC. Given the complexity of the data surrounding any target, efficient and intuitive visualization has been a high priority, to enable users to quickly navigate & summarize search results and rapidly identify patterns. A critical feature of the interface is the ability to perform flexible search and subsequent drill down of search results. Underlying the interface is a RESTful API that provides programmatic access to all KMC data, allowing for easy consumption in user applications.
This record is not implemented by any policy.
Record Maintainer
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Funds
NIH Common Fund, USA (Government body)
Maintains
Grant Number(s)
U54CA189205 (Illuminating the Druggable Genome Knowledge Management Center, Tudor Oprea, PI) (NIH Common Fund, USA)