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Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins

Abbreviation:PANTHER

General Information

The PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System is a unique resource that classifies genes by their functions, using published scientific experimental evidence and evolutionary relationships to predict function even in the absence of direct experimental evidence.

Homepage http://www.pantherdb.org

Countries that developed this resource United States

Created in 2002

Taxonomic range

All

Knowledge Domains

Subjects

User-defined Tags

Evolutionary relationship between proteins via sequence similarity

How to cite this record FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Oct 27 2021 12:51 a.m.

Publication for citation PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements. Mi H,Huang X,Muruganujan A,Tang H,Mills C,Kang D,Thomas PD; Nucleic Acids Res ; 2016; 10.1093/nar/gkw1138;

Record updated: Nov. 21, 2018, 10:01 a.m. by The FAIRsharing Team.

Show edit history

Edits to 'https://fairsharing.org/FAIRsharing.ty3dqs' by 'The FAIRsharing Team' at 10:01, 21 Nov 2018 (approved):

	'domains' has been modified:
		Before:
			Biological evolution
			Classification
			Evidence
			Evolutionary relationship between proteins via sequence similarity
			Function analysis
			Gene
			Life Science
			Pathway model
			Protein
			Sequence similarity
		After:
			Amino acid sequence
			Biological evolution
			Classification
			Evidence
			Evolutionary relationship between proteins via sequence similarity
			Function analysis
			Gene
			Life Science
			Pathway model
			Protein
			Sequence similarity
		Added:
			Amino acid sequence
		Removed:

Edits to 'https://fairsharing.org/FAIRsharing.ty3dqs' by 'The FAIRsharing Team' at 19:22, 04 Aug 2018 (approved):

	'licences' has been modified:
		Before:
			Attribution required||Data
			Panther DB Data Policies and Disclaimer|http://www.pantherdb.org/terms/disclaimer.jsp|Data
			Panther Website Privacy Policy|http://www.pantherdb.org/terms/privacyPolicy.jsp|Data
			Publicly available data||Data
		After:
			Panther DB Data Policies and Disclaimer|http://www.pantherdb.org/terms/disclaimer.jsp|Data
			Panther Website Privacy Policy|http://www.pantherdb.org/terms/privacyPolicy.jsp|Data
		Added:
		Removed:
			Attribution required||Data
			Publicly available data||Data

	'publications' has been modified:
		Before:
			PANTHER: a library of protein families and subfamilies indexed by function.|Thomas PD., Campbell MJ., Kejariwal A., Mi H., Karlak B., Daverman R., Diemer K., Muruganujan A., Narechania A., |Genome Res.|2003
		After:
			PANTHER: a library of protein families and subfamilies indexed by function.|Thomas PD., Campbell MJ., Kejariwal A., Mi H., Karlak B., Daverman R., Diemer K., Muruganujan A., Narechania A., |Genome Res.|2003
			PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements.|Mi H,Huang X,Muruganujan A,Tang H,Mills C,Kang D,Thomas PD|Nucleic Acids Res|2016
			Large-scale gene function analysis with the PANTHER classification system.|Mi H,Muruganujan A,Casagrande JT,Thomas PD|Nat Protoc|2013
			PANTHER-PSEP: predicting disease-causing genetic variants using position-specific evolutionary preservation.|Tang H,Thomas PD|Bioinformatics|2016
			PANTHER pathway: an ontology-based pathway database coupled with data analysis tools.|Mi H,Thomas P|Methods Mol Biol|2009
		Added:
			PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements.|Mi H,Huang X,Muruganujan A,Tang H,Mills C,Kang D,Thomas PD|Nucleic Acids Res|2016
			Large-scale gene function analysis with the PANTHER classification system.|Mi H,Muruganujan A,Casagrande JT,Thomas PD|Nat Protoc|2013
			PANTHER-PSEP: predicting disease-causing genetic variants using position-specific evolutionary preservation.|Tang H,Thomas PD|Bioinformatics|2016
			PANTHER pathway: an ontology-based pathway database coupled with data analysis tools.|Mi H,Thomas P|Methods Mol Biol|2009
		Removed:

Edits to 'https://fairsharing.org/FAIRsharing.ty3dqs' by 'The FAIRsharing Team' at 09:31, 04 Aug 2018 (approved):

	'miriam_id' has been modified:
		Before: None
		After: 

	'contact' has been modified:
		Before: None
		After: General contact

	'tools' has been modified:
		Before:
			Gene list analysis||http://www.pantherdb.org/
			PANTHER scoring||http://www.pantherdb.org/tools/hmmScoreForm.jsp
			Evolutionary analysis of coding SNPS||http://www.pantherdb.org/tools/csnpScoreForm.jsp
			BLAST||http://www.pantherdb.org/tools/hmmScoreForm.jsp?
		After:
			BLAST||http://www.pantherdb.org/tools/hmmScoreForm.jsp?
		Added:
		Removed:
			Gene list analysis||http://www.pantherdb.org/
			PANTHER scoring||http://www.pantherdb.org/tools/hmmScoreForm.jsp
			Evolutionary analysis of coding SNPS||http://www.pantherdb.org/tools/csnpScoreForm.jsp

	'dataProcesses' has been modified:
		Before:
			Download
			Browse
		After:
			Download
			Browse
			Panther scoring
			Gene List Analysis
			Evolutionary analysis of coding SNPs
		Added:
			Panther scoring
			Gene List Analysis
			Evolutionary analysis of coding SNPs
		Removed:

In Collections

Systems Medicine

Open Science Prize

Support

General

contact form	http://www.pantherdb.org/feedback.jsp
help	http://www.pantherdb.org/help/PANTHERhel ...

Additional Information

Contact

General contact

Tools

BLAST

http://www.pantherdb.org/tools/hmmScoreForm.jsp?

Access / Retrieve Data

Conditions of Use

Applies to: Data use

Data Access

Download	http://www.pantherdb.org/downloads/index.jsp
Browse	http://www.pantherdb.org/data/
Panther scoring	http://www.pantherdb.org/tools/hmmScoreForm.jsp
Gene List Analysis	http://www.pantherdb.org/
Evolutionary analysis of coding SNPs	http://www.pantherdb.org/tools/csnpScoreForm.jsp

Publications

PANTHER: a library of protein families and subfamilies indexed by function.

Thomas PD., Campbell MJ., Kejariwal A., Mi H., Karlak B., Daverman R., Diemer K., Muruganujan A., Narechania A.,
Genome Res. 2003