databases > DOI:10.25504/FAIRsharing.zvh04m

ready Alternative Poly(A) Sites database

Abbreviation:APASdb

General Information
APASdb can visualize the precise map and usage quantification of different APA isoforms for all genes. The datasets are deeply profiled by the sequencing alternative polyadenylation sites (SAPAS) method capable of high-throughput sequencing 3'-ends of polyadenylated transcripts. Thus, APASdb details all the heterogeneous cleavage sites downstream of poly(A) signals, and maintains near complete coverage for APA sites. Furthermore, APASdb provides the quantification of a given APA variant among transcripts with different APA sites by computing their corresponding normalized-reads. In addition, APASdb supports URL-based retrieval, browsing and display of exon-intron structure, poly(A) signals, poly(A) sites location and usage reads, and 3'-untranslated regions (3'-UTRs). Currently, APASdb involves APA in various biological processes and diseases in human, mouse and zebrafish.




How to cite this record FAIRsharing.org: APASdb; Alternative Poly(A) Sites database; DOI: https://doi.org/10.25504/FAIRsharing.zvh04m; Last edited: Feb. 22, 2018, 2:58 p.m.; Last accessed: Nov 13 2018 5 p.m.


Record updated: Nov. 18, 2016, 4:29 p.m. by The FAIRsharing Team.

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Publications

APASdb: a database describing alternative poly(A) sites and selection of heterogeneous cleavage sites downstream of poly(A) signals.

You L, Wu J, Feng Y, Fu Y, Guo Y, Long L, Zhang H, Luan Y, Tian P, Chen L, Huang G, Huang S, Li Y, Li J, Chen C, Zhang Y, Chen S, Xu A
Nucleic Acid Research 2014

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  • 2011CB946101 (National Basic Research Program of China, Beijing, China)

  • 2013CB835304 (National Basic Research Program of China, Beijing, China)

  • 2013CB917800 (National Basic Research Program of China, Beijing, China)