How to cite this record FAIRsharing.org: HotRegion; HotRegion; DOI: https://doi.org/10.25504/FAIRsharing.m4a6d3; Last edited: Jan. 8, 2019, 1:13 p.m.; Last accessed: Dec 08 2021 12:43 p.m.
Record updated: Sept. 26, 2016, 10:27 a.m. by The FAIRsharing Team.
Edits to 'https://fairsharing.org/FAIRsharing.m4a6d3' by 'The FAIRsharing Team' at 10:27, 26 Sep 2016 (approved): 'description' has been modified: Before: Database of interaction Hotspots across the proteome. After: Database of interaction Hotspots across the proteome. Hot spots are energetically important residues at protein interfaces and they are not randomly distributed across the interface but rather clustered. These clustered hot spots form hot regions. HotRegion, provides information of these interfaces by using predicted hot spot residues, and structural properties of these interface residues such as pair potentials of interface residues, accessible surface area (ASA) and relative ASA values of interface residues of both monomer and complex forms of proteins. Also, the 3D visualization of the interface and interactions among hot spot residues are provided.
Edits to 'https://fairsharing.org/FAIRsharing.m4a6d3' by 'The FAIRsharing Team' at 10:24, 26 Sep 2016 (approved): 'description' has been modified: Before: Database of interaction Hotspots After: Database of interaction Hotspots across the proteome.
Edits to 'https://fairsharing.org/FAIRsharing.m4a6d3' by 'The FAIRsharing Team' at 10:23, 26 Sep 2016 (approved): 'name' has been modified: Before: HotRegion: A database of hot spot clusters After: HotRegion
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Hot regions in protein--protein interactions: the organization and contribution of structurally conserved hot spot residues.
Keskin O., Ma B., Nussinov R.,
J. Mol. Biol. 2005
Analysis of hot region organization in hub proteins.
Cukuroglu E., Gursoy A., Keskin O.,
Ann Biomed Eng 2010
HotRegion: a database of predicted hot spot clusters.
Cukuroglu E,Gursoy A,Keskin O
Nucleic Acids Res 2011
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109E207 (TBTAK, Ankara, Turkey)
109T343 (TBTAK, Ankara, Turkey)