Edits to 'https://fairsharing.org/FAIRsharing.yfk4w2' by 'panelapp' at 15:34, 23 Jul 2020 (approved):
'description' has been modified:
Before: Genomics England PanelApp is a publically-available knowledgebase that allows virtual gene panels related to human disorders to be created, stored and queried. It includes a crowdsourcing tool that allows genes to be added or reviewed by experts throughout the worldwide scientific community, providing an opportunity for the standardisation of gene panels, and a consensus on which genes have sufficient evidence for disease association.
The diagnostic grade ?Green? genes and their modes of inheritance in the Version 1+ PanelApp virtual gene panels are used to direct the variant tiering process for the interpretation of genomes in the 100,000 Genomes Project. As panels in PanelApp are publically available, they can also be utilised by others. Experts are asked to register (https://panelapp.genomicsengland.co.uk/accounts/registration/) in order to review and rate the genes on the panel to indicate whether there is a diagnostic-grade level of evidence for the gene to be implicated in a given disease. Bioinformaticians can access the data via the PanelApp API (https://panelapp.genomicsengland.co.uk/#!API). More detailed background information, instructions and updates can be found on the PanelApp homepage tabs.
After: Genomics England PanelApp is a publically-available knowledgebase that allows virtual gene panels related to human disorders to be created, stored and queried. It includes a crowdsourcing tool that allows genes to be added or reviewed by experts throughout the worldwide scientific community, providing an opportunity for the standardisation of gene panels, and a consensus on which genes have sufficient evidence for disease association.
The diagnostic grade ?Green? genes and their modes of inheritance in the Version 1+ PanelApp virtual gene panels are used to direct the variant tiering process for the interpretation of genomes in the 100,000 Genomes Project and for the National Health Service England Genomic Medicine Service. As panels in PanelApp are publically available, they can also be utilised by others. Experts are asked to register (https://panelapp.genomicsengland.co.uk/accounts/registration/) in order to review and rate the genes on the panel to indicate whether there is a diagnostic-grade level of evidence for the gene to be implicated in a given disease. Bioinformaticians can access the data via the PanelApp API (https://panelapp.genomicsengland.co.uk/#!API). More detailed background information, instructions and updates can be found on the PanelApp homepage tabs.
Edits to 'https://fairsharing.org/FAIRsharing.yfk4w2' by 'The FAIRsharing Team' at 20:29, 20 Jul 2020 (approved):
'user_defined_tags' has been modified:
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COVID-19
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COVID-19
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'publications' has been modified:
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PanelApp crowdsources expert knowledge to establish consensus diagnostic gene panels.|Martin AR,Williams E,Foulger RE,Leigh S,Daugherty LC,Niblock O,Leong IUS,Smith KR,Gerasimenko O,Haraldsdottir E,Thomas E,Scott RH,Baple E,Tucci A,Brittain H,de Burca A,Ibanez K,Kasperaviciute D,Smedley D,Caulfield M,Rendon A,McDonagh EM|Nat Genet|2019
Added:
PanelApp crowdsources expert knowledge to establish consensus diagnostic gene panels.|Martin AR,Williams E,Foulger RE,Leigh S,Daugherty LC,Niblock O,Leong IUS,Smith KR,Gerasimenko O,Haraldsdottir E,Thomas E,Scott RH,Baple E,Tucci A,Brittain H,de Burca A,Ibanez K,Kasperaviciute D,Smedley D,Caulfield M,Rendon A,McDonagh EM|Nat Genet|2019
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Edits to 'https://fairsharing.org/FAIRsharing.yfk4w2' by 'panelapp' at 12:12, 27 Apr 2020 (approved):
'contact' has been modified:
Before: Ellen McDonagh
After: PanelApp team
'description' has been modified:
Before: Genomics England PanelApp is a publically-available knowledgebase that allows virtual gene panels related to human disorders to be created, stored and queried. It includes a crowdsourcing tool that allows genes to be added or reviewed by experts throughout the worldwide scientific community, providing an opportunity for the standardisation of gene panels, and a consensus on which genes have sufficient evidence for disease association.
The diagnostic grade ?Green? genes and their modes of inheritance in the Version 1+ PanelApp virtual gene panels are used to direct the variant tiering process for the interpretation of genomes in the 100,000 Genomes Project. As panels in PanelApp are publically available, they can also be utilised by others. Experts are asked to register (https://panelapp.genomicsengland.co.uk/accounts/registration/) in order to review and rate the genes on the panel to indicate whether there is a diagnostic-grade level of evidence for the gene to be implicated in a given disease. Bioinformaticians can access the data via the PanelApp webservices (https://panelapp.genomicsengland.co.uk/#!Webservices). More detailed background information, instructions and updates can be found on the PanelApp homepage tabs.
After: Genomics England PanelApp is a publically-available knowledgebase that allows virtual gene panels related to human disorders to be created, stored and queried. It includes a crowdsourcing tool that allows genes to be added or reviewed by experts throughout the worldwide scientific community, providing an opportunity for the standardisation of gene panels, and a consensus on which genes have sufficient evidence for disease association.
The diagnostic grade ?Green? genes and their modes of inheritance in the Version 1+ PanelApp virtual gene panels are used to direct the variant tiering process for the interpretation of genomes in the 100,000 Genomes Project. As panels in PanelApp are publically available, they can also be utilised by others. Experts are asked to register (https://panelapp.genomicsengland.co.uk/accounts/registration/) in order to review and rate the genes on the panel to indicate whether there is a diagnostic-grade level of evidence for the gene to be implicated in a given disease. Bioinformaticians can access the data via the PanelApp API (https://panelapp.genomicsengland.co.uk/#!API). More detailed background information, instructions and updates can be found on the PanelApp homepage tabs.
'contactORCID' has been modified:
Before: 0000-0001-5806-6174
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Edits to 'https://fairsharing.org/FAIRsharing.yfk4w2' by 'The FAIRsharing Team' at 09:07, 22 Apr 2020 (approved):
'supportLinks' has been modified:
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help|https://panelapp.genomicsengland.co.uk/
twitter|@GenomicsEngland
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FAQ|https://panelapp.genomicsengland.co.uk/#!FAQs
blog|https://panelapp.genomicsengland.co.uk/#!News
help|https://panelapp.genomicsengland.co.uk/
help|https://panelapp.genomicsengland.co.uk/#!Navigating
online documentation|https://panelapp.genomicsengland.co.uk/#!Guidelines
twitter|@GenomicsEngland
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FAQ|https://panelapp.genomicsengland.co.uk/#!FAQs
blog|https://panelapp.genomicsengland.co.uk/#!News
help|https://panelapp.genomicsengland.co.uk/#!Navigating
online documentation|https://panelapp.genomicsengland.co.uk/#!Guidelines
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PanelApp Terms of Use|https://panelapp.genomicsengland.co.uk/media/files/GEL_-_PanelApp_Terms_of_Use_December_2019.pdf|Data
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PanelApp Terms of Use|https://panelapp.genomicsengland.co.uk/media/files/GEL_-_PanelApp_Terms_of_Use_December_2019.pdf|Data
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Genomics
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Epidemiology
Genomics
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Epidemiology
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Browse & search genes and genomic entities
Browse panels
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Browse & search genes and genomic entities
Browse panels
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Other|https://panelapp.genomicsengland.co.uk/#!API|PanelApp API
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Other|https://panelapp.genomicsengland.co.uk/#!API|PanelApp API
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Edits to 'https://fairsharing.org/FAIRsharing.yfk4w2' by 'emcdonagh' at 15:28, 14 Feb 2018 (approved):
'supportLinks' has been modified:
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https://bioinfo.extge.co.uk/crowdsourcing/PanelApp/
@GenomicsEngland
@PanelApp
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https://panelapp.genomicsengland.co.uk/
@GenomicsEngland
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https://panelapp.genomicsengland.co.uk/
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https://bioinfo.extge.co.uk/crowdsourcing/PanelApp/
@PanelApp
Edits to 'https://fairsharing.org/FAIRsharing.yfk4w2' by 'emcdonagh' at 15:25, 14 Feb 2018 (approved):
'description' has been modified:
Before: The 100,000 Genomes Project database is publicly available via the PanelApp tool/app and gene panels can be viewed and downloaded from the website, or queried using the PanelApp web services. PanelApp is a crowdsourcing tool to allow gene panels to be shared, downloaded, viewed and evaluated by the Scientific Community. Gene panels were initially established for all the rare diseases in the 100,000 Genomes Project. The full list of available panels is available here: https://bioinfo.extge.co.uk/crowdsourcing/PanelApp/PanelBrowser. Experts are asked to register in order to review and rate the genes on the panel to indicate whether there is a diagnostic-grade level of evidence for the gene to be implicated in a given disease. Guidelines for the level of evidence are provided on the Gene Panel Guidelines and Principles tab on the homepage. More detailed background information, instructions and updates can be found on the PanelApp homepage tabs.
After: Genomics England PanelApp is a publically-available knowledgebase that allows virtual gene panels related to human disorders to be created, stored and queried. It includes a crowdsourcing tool that allows genes to be added or reviewed by experts throughout the worldwide scientific community, providing an opportunity for the standardisation of gene panels, and a consensus on which genes have sufficient evidence for disease association. The diagnostic grade Green genes and their modes of inheritance in the Version 1+ PanelApp virtual gene panels are used to direct the variant tiering process for the interpretation of genomes in the 100,000 Genomes Project. As panels in PanelApp are publically available|they can also be utilised by others. Experts are asked to register (https://panelapp.genomicsengland.co.uk/accounts/registration/) in order to review and rate the genes on the panel to indicate whether there is a diagnostic-grade level of evidence for the gene to be implicated in a given disease. Bioinformaticians can access the data via the PanelApp webservices (https://panelapp.genomicsengland.co.uk/#!Webservices). More detailed background information|instructions and updates can be found on the PanelApp homepage tabs.