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ready MethylomeDB

General Information
This resource details DNA methylation profiles in human and mouse brain. This database includes genome-wide DNA methylation profiles for human and mouse brains. The DNA methylation profiles were generated by Methylation Mapping Analysis by Paired-end Sequencing (Methyl-MAPS) method and analyzed by Methyl-Analyzer software package. The methylation profiles cover over 80% CpG dinucleotides in human and mouse brains in single-CpG resolution. The integrated genome browser (modified from UCSC Genome Browser allows users to browse DNA methylation profiles in specific genomic loci, to search specific methylation patterns, and to compare methylation patterns between individual samples.


Countries that developed this resource United States

Created in 2011


How to cite this record MethylomeDB; MethylomeDB; DOI:; Last edited: Jan. 8, 2019, 1:14 p.m.; Last accessed: Sep 20 2021 3:48 a.m.

Record updated: July 27, 2018, 11:06 a.m. by The FAIRsharing Team.

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MethylomeDB: a database of DNA methylation profiles of the brain.

Xin Y., Chanrion B., O'Donnell AH., Milekic M., Costa R., Ge Y., Haghighi FG.,
Nucleic Acids Res. 2012

View Paper (PubMed)

Distinct DNA methylation changes highly correlated with chronological age in the human brain.

Hernandez DG,Nalls MA,Gibbs JR,Arepalli S,van der Brug M,Chong S,Moore M,Longo DL,Cookson MR,Traynor BJ,Singleton AB
Hum Mol Genet 2011

View Paper (PubMed) View Publication

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Grant Number(s)

  • Z01 AG000932-02 (National Institute on Aging (NIA), Bethesda, MD, USA)