FAIRsharing is here! From our first incarnation, BioSharing.org, which focussed on the life sciences, we are growing into FAIRsharing.org, to serve users across all disciplines.

ready HotRegion

General Information
Database of interaction Hotspots across the proteome. Hot spots are energetically important residues at protein interfaces and they are not randomly distributed across the interface but rather clustered. These clustered hot spots form hot regions. HotRegion, provides information of these interfaces by using predicted hot spot residues, and structural properties of these interface residues such as pair potentials of interface residues, accessible surface area (ASA) and relative ASA values of interface residues of both monomer and complex forms of proteins. Also, the 3D visualization of the interface and interactions among hot spot residues are provided.

Homepage http://prism.ccbb.ku.edu.tr/hotregion

Developed in Turkey

Created in 2011

Taxonomic range





Record updated: Sept. 26, 2016, 10:27 a.m. by The FAIRsharing Team.



Tools

    No tools defined


Access / Retrieve Data

Conditions of Use


Data Access




Connectivity
Related Standards

Reporting Guidelines

No guidelines defined

Terminology Artifacts

No semantic standards defined

Models and Formats


Related Databases

No related databases defined


Implementing Policies

This record is not implemented by any policy.



Publications

Hot regions in protein--protein interactions: the organization and contribution of structurally conserved hot spot residues.

Keskin O., Ma B., Nussinov R.,
J. Mol. Biol. 2005

View Paper (PubMed) View Paper (DOI)

Analysis of hot region organization in hub proteins.

Cukuroglu E., Gursoy A., Keskin O.,
Ann Biomed Eng 2010

View Paper (PubMed) View Paper (DOI)

HotRegion: a database of predicted hot spot clusters.

Cukuroglu E,Gursoy A,Keskin O
Nucleic Acids Res 2011

View Paper (PubMed) View Paper (DOI)

HotRegion: a database of predicted hot spot clusters.

Cukuroglu E,Gursoy A,Keskin O
Nucleic Acids Res 2011

View Paper (PubMed) View Paper (DOI)