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ready Pfam Protein Families

Abbreviation:Pfam

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General Information
The Pfam database is a large collection of protein families, each represented by multiple sequence alignments and hidden Markov models (HMMs). Proteins are generally composed of one or more functional regions, commonly termed domains. Different combinations of domains give rise to the diverse range of proteins found in nature. The identification of domains that occur within proteins can therefore provide insights into their function. Pfam also generates higher-level groupings of related entries, known as clans. A clan is a collection of Pfam entries which are related by similarity of sequence, structure or profile-HMM.


This record replaces or incorporates the following deprecated resources:

Homepage http://pfam.xfam.org/

Developed in United Kingdom

Created in 1996

Taxonomic range




In the following recommendations:




How to cite this record FAIRsharing.org: Pfam; Pfam Protein Families; DOI: 10.25504/FAIRsharing.y3scf6; Last edited: Feb. 22, 2018, 2:44 p.m.; Last accessed: Jun 18 2018 4:34 p.m.


Record updated: Aug. 12, 2016, 2:16 p.m. by The FAIRsharing Team.


In Collections
ELIXIR node contributed resources



Access / Retrieve Data

Conditions of Use

Applies to: Data use

Data Access

file download(txt) No link recorded
SQL database dump No link recorded
DAS server No link recorded
FTP download ftp://ftp.ebi.ac.uk/pub/databases/Pfam
browse http://pfam.xfam.org/browse
search http://pfam.xfam.org/search#tabview=tab1

REST Web Services

REST web service http://pfam.xfam.org/help#tabview=tab10


Publications

The Pfam protein families database.

Finn RD., Mistry J., Tate J., Coggill P., Heger A., Pollington JE., Gavin OL., Gunasekaran P., Ceric G., Forslund K., Holm L., Sonnhammer EL., Eddy SR., Bateman A.,
Nucleic Acids Res. 2010

View Paper (PubMed) View Paper (DOI)

The Pfam protein families database: towards a more sustainable future.

Finn RD,Coggill P,Eberhardt RY,Eddy SR,Mistry J,Mitchell AL,Potter SC,Punta M,Qureshi M,Sangrador-Vegas A,Salazar GA,Tate J,Bateman A
Nucleic Acids Res 2015

View Paper (PubMed) View Paper (DOI)

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Maintains

Grant Number(s)

  • 108433/Z/15/Z (The Wellcome Trust)

  • BB/L024136/1 (Biotechnology and Biological Sciences Research Council (BBSRC), UK)

  • WT077044/Z/05/Z (The Wellcome Trust)