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ready Polymorphism in microRNAs and their TargetSites

Abbreviation:PolymiRTS

General Information
PolymiRTS (Polymorphism in microRNAs and their TargetSites) is a database of naturally occurring DNA variations in microRNA (miRNA) seed regions and miRNA target sites. MicroRNAs pair to the transcripts of protein-coding genes and cause translational repression or mRNA destabilization. SNPs and INDELs in miRNAs and their target sites may affect miRNA-mRNA interaction, and hence affect miRNA-mediated gene repression.



Record updated: Dec. 2, 2016, 4:25 p.m. by The FAIRsharing Team.


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Grant Number(s)

  • 0830134N (American Heart Association)

  • AA014425 (National Institutes of Health)

  • AI019782 (National Institutes of Health)

  • AI081050 (National Institutes of Health)

  • DA021131 (National Institutes of Health)

  • HD052472 (National Institutes of Health)

  • NR009270 (National Institutes of Health)

  • W81XHW-05-01-0227 (U.S. Department of Defense)


Publications

PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits.

Bao L., Zhou M., Wu L., Lu L., Goldowitz D., Williams RW., Cui Y.,
Nucleic Acids Res. 2007

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PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways.

Bhattacharya A,Ziebarth JD,Cui Y
Nucleic Acids Res 2013

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PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits.

Ziebarth JD,Bhattacharya A,Chen A,Cui Y
Nucleic Acids Res 2011

View Paper (PubMed) View Paper (DOI)