databases > DOI:10.25504/FAIRsharing.pn1sr5
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General Information
Rhea is a comprehensive and non-redundant resource of expert-curated chemical and transport reactions of biological interest. Rhea can be used for enzyme annotation, genome-scale metabolic modeling and omics-related analysis. Rhea describes enzyme-catalyzed reactions covering the IUBMB Enzyme Nomenclature list as well as additional reactions, including spontaneously occurring reactions. Rhea is built on ChEBI (Chemical Entities of Biological Interest) ontology of small molecules to describe its reaction participants. Since December 2018, Rhea is the standard for enzyme annotation in UniProt.


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How to cite this record FAIRsharing.org: Rhea; Rhea; DOI: https://doi.org/10.25504/FAIRsharing.pn1sr5; Last edited: May 19, 2020, 3:36 p.m.; Last accessed: Sep 18 2020 7:39 a.m.

Publication for citation  Updates in Rhea: SPARQLing biochemical reaction data. Lombardot T, Morgat A, Axelsen KB, Aimo L, Hyka-Nouspikel N, Niknejad A, Ignatchenko A, Xenarios I, Coudert E, Redaschi N, Bridge A; Nucleic Acids Res ; 2018; 10.1093/nar/gky876;


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Record updated: May 19, 2020, 1:52 p.m. by amorgat.

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Publications

Updates in Rhea--a manually curated resource of biochemical reactions.

Morgat A, Axelsen KB, Lombardot T, Alcántara R, Aimo L, Zerara M, Niknejad A, Belda E, Hyka-Nouspikel N, Coudert E, Redaschi N, Bougueleret L, Steinbeck C, Xenarios I, Bridge A.
Nucleic Acids Res. 2014

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Rhea--a manually curated resource of biochemical reactions.

Alcantara R,Axelsen KB,Morgat A,Belda E,Coudert E,Bridge A,Cao H,de Matos P,Ennis M,Turner S,Owen G,Bougueleret L,Xenarios I,Steinbeck C
Nucleic Acids Res. 2011

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Updates in Rhea - an expert curated resource of biochemical reactions.

Morgat A, Lombardot T, Axelsen KB, Aimo L, Niknejad A, Hyka-Nouspikel N, Coudert E, Pozzato M, Pagni M, Moretti S, Rosanoff S, Onwubiko J, Bougueleret L, Xenarios I, Redaschi N, Bridge A.
Nucleic Acids Res. 2017

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Updates in Rhea: SPARQLing biochemical reaction data.

Lombardot T, Morgat A, Axelsen KB, Aimo L, Hyka-Nouspikel N, Niknejad A, Ignatchenko A, Xenarios I, Coudert E, Redaschi N, Bridge A
Nucleic Acids Res 2018

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Enzyme annotation in UniProtKB using Rhea

Morgat A, Lombardot T, Coudert E, Axelsen K, Neto TB, Gehant S, Bansal P, Bolleman J, Gasteiger E, de Castro E, Baratin D, Pozzato M, Xenarios I, Poux S, Redaschi N, Bridge A and the UniProt Consortium
Bioinformatics 2019

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