Record updated: Feb. 4, 2021, 2:40 p.m. by The FAIRsharing Team.

Edits to 'https://fairsharing.org/FAIRsharing.6c4fvf' by 'The FAIRsharing Team' at 14:40, 04 Feb 2021 (approved):

	'standardsImplemented' has been modified:
		Before:
			Portable Network Graphics
			Hyper Text Markup Language
		After:
			Portable Network Graphics
		Added:
		Removed:
			Hyper Text Markup Language

	'supportLinks' has been modified:
		Before:
			FAQ|http://tdrtargets.org/faq
			email|info@tdrtargets.org
			online documentation|http://tdrtargets.org/documentation
			wikipedia|https://en.wikipedia.org/wiki/TDR_Targets
		After:
			email|info@tdrtargets.org
			help|https://tdrtargets.org/tutorials
			help|https://tdrtargets.org/manual
			online documentation|https://tdrtargets.org/datasummary
			wikipedia|https://en.wikipedia.org/wiki/TDR_Targets
		Added:
			help|https://tdrtargets.org/tutorials
			help|https://tdrtargets.org/manual
			online documentation|https://tdrtargets.org/datasummary
		Removed:
			FAQ|http://tdrtargets.org/faq
			online documentation|http://tdrtargets.org/documentation

	'description' has been modified:
		Before: Identification and ranking of targets and bioactive compounds against neglected tropical diseases. TDR Targets integrates chemical and genomic information and allows users to prioritize targets and compounds to develop and repurpose new drugs and chemical tools for human pathogens. 

The TDR Target Project was started in 2005 after a call for applications was launched by TDR (Special Programme for Research and Training in Tropical Diseases (UNICEF / UNDP / World Bank / WHO, http://www.who.int/tdr)). As a result, the TDR Targets Database was established to help develop a portfolio of candidate drug targets for 5 major human pathogens. This shortly turned into a resource for prioritizing targets for neglected tropical diseases. TDR Targets is led and run by the Trypanosomatics group at IIB-UNSAM (Argentina, https://trypanosomatics.org) with help with external collaborators worldwide.

		After: TDR Targets integrates chemical and genomic information and allows users to prioritize targets and compounds to develop and repurpose new drugs and chemical tools for human pathogens. 

The TDR Target Project was started in 2005 after a call for applications was launched by TDR (Special Programme for Research and Training in Tropical Diseases). As a result, the TDR Targets Database was established to help develop a portfolio of candidate drug targets for 5 major human pathogens. This then became a resource for prioritizing targets for neglected tropical diseases. TDR Targets is led and run by the Trypanosomatics group at IIB-UNSAM (Argentina, https://trypanosomatics.org) with help with external collaborators worldwide.


	'licences' has been modified:
		Before:
		After:
			TDR Targets Data Access Policy|https://tdrtargets.org/about|Data
		Added:
			TDR Targets Data Access Policy|https://tdrtargets.org/about|Data
		Removed:

	'onto_disciplines' has been modified:
		Before:
			Life Science
		After:
			Drug Development
			Drug Discovery
			Drug Repositioning
			Life Science
		Added:
			Drug Development
			Drug Discovery
			Drug Repositioning
		Removed:

	'dataProcesses' has been modified:
		Before:
			6-9 months, data release, 
			register, data access, http://tdrtargets.org/user/register
			browse, data access, http://tdrtargets.org/survey
			search, data access, http://tdrtargets.org/survey
			manual curation, data curation, 
			versioning of by revision control system [web application code (atomic changes)], data versioning, 
			access to historical database dumps (SQL dumps) possible, data versioning, 
			file download(CSV,txt,tab-delimited), data access, 
			submit, data curation, http://tdrtargets.org/survey
		After:
			register, data access, https://tdrtargets.org/user/register
			Search for Drugs/Compounds, data access, https://tdrtargets.org/drugs
			Targets Search, data access, https://tdrtargets.org/targets/search
			Release Information, data release, https://tdrtargets.org/releases
		Added:
			register, data access, https://tdrtargets.org/user/register
			Search for Drugs/Compounds, data access, https://tdrtargets.org/drugs
			Targets Search, data access, https://tdrtargets.org/targets/search
			Release Information, data release, https://tdrtargets.org/releases
		Removed:
			6-9 months, data release, 
			register, data access, http://tdrtargets.org/user/register
			browse, data access, http://tdrtargets.org/survey
			search, data access, http://tdrtargets.org/survey
			manual curation, data curation, 
			versioning of by revision control system [web application code (atomic changes)], data versioning, 
			access to historical database dumps (SQL dumps) possible, data versioning, 
			file download(CSV,txt,tab-delimited), data access, 
			submit, data curation, http://tdrtargets.org/survey

	'user_defined_tags' has been modified:
		Before:
			Atomic composition
			Drug-like compound
			Number of flexible bonds
			Rule of five compliance
		After:
			Atomic composition
			Drug Target
			Drug-like compound
			Number of flexible bonds
			Rule of five compliance
		Added:
			Drug Target
		Removed:

	'onto_domains' has been modified:
		Before:
			Annotation
			DNA sequence
			EC number
			GO-term enrichment report
			Gene expression data
			Gene name
			Genome annotation
			Pathway or network prediction
			Sequence length
			acceptor
			antigen
			bioactivity assay
			chemical descriptor
			chemical entity
			disease
			donor
			gene
			glycosylphosphatidylinositol anchor
			logP descriptor
			molecular weight
			proton
			signal_peptide
			structure
		After:
			Annotation
			DNA sequence
			EC number
			GO-term enrichment report
			Gene expression data
			Gene name
			Genome annotation
			Prediction and recognition
			Sequence length
			Structure
			acceptor
			antigen
			bioactivity assay
			chemical descriptor
			chemical entity
			disease
			donor
			drug
			gene
			glycosylphosphatidylinositol anchor
			logP descriptor
			molecular weight
			proton
			signal_peptide
			structure
		Added:
			Prediction and recognition
			Structure
			drug
		Removed:
			Pathway or network prediction

	'publications' has been modified:
		Before:
			Genomic-scale prioritization of drug targets: the TDR Targets database.|Agero F., Al-Lazikani B., Aslett M., Berriman M., Buckner FS., Campbell RK., Carmona S., Carruthers IM., Chan AW., Chen F., Crowther GJ., Doyle MA., Hertz-Fowler C., Hopkins AL., McAllister G., Nwaka S., Overington JP., Pain A., Paolini GV., Pieper U., Ralph SA., Riechers A., Roos DS., Sali A., Shanmugam D., Suzuki T., Van Voorhis WC., Verlinde CL., |Nat Rev Drug Discov|2008
			Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.|Crowther GJ., Shanmugam D., Carmona SJ., Doyle MA., Hertz-Fowler C., Berriman M., Nwaka S., Ralph SA., Roos DS., Van Voorhis WC., Agero F., |PLoS Negl Trop Dis|2010
			TDR Targets: a chemogenomics resource for neglected diseases.|Magarinos MP,Carmona SJ,Crowther GJ,Ralph SA,Roos DS,Shanmugam D,Van Voorhis WC,Aguero F|Nucleic Acids Res|2011
		After:
			Genomic-scale prioritization of drug targets: the TDR Targets database.|Agero F., Al-Lazikani B., Aslett M., et al.|Nat Rev Drug Discov|2008
			Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.|Crowther GJ., Shanmugam D., Carmona SJ., Doyle MA., Hertz-Fowler C., Berriman M., Nwaka S., Ralph SA., Roos DS., Van Voorhis WC., Agero F., |PLoS Negl Trop Dis|2010
			TDR Targets: a chemogenomics resource for neglected diseases.|Magarinos MP,Carmona SJ,Crowther GJ,Ralph SA,Roos DS,Shanmugam D,Van Voorhis WC,Aguero F|Nucleic Acids Res|2011
		Added:
			Genomic-scale prioritization of drug targets: the TDR Targets database.|Agero F., Al-Lazikani B., Aslett M., et al.|Nat Rev Drug Discov|2008
		Removed:
			Genomic-scale prioritization of drug targets: the TDR Targets database.|Agero F., Al-Lazikani B., Aslett M., Berriman M., Buckner FS., Campbell RK., Carmona S., Carruthers IM., Chan AW., Chen F., Crowther GJ., Doyle MA., Hertz-Fowler C., Hopkins AL., McAllister G., Nwaka S., Overington JP., Pain A., Paolini GV., Pieper U., Ralph SA., Riechers A., Roos DS., Sali A., Shanmugam D., Suzuki T., Van Voorhis WC., Verlinde CL., |Nat Rev Drug Discov|2008

            

Edits to 'https://fairsharing.org/FAIRsharing.6c4fvf' by 'fernan' at 15:34, 21 Oct 2019 (approved):

	'organizations' has been modified:
		Before:
			University of Washington, USA|https://www.washington.edu/|Maintains
		After:
			University of Washington, USA|https://www.washington.edu/|Undefined
			Instituto de Investigaciones Biotecnolgicas, Universidad de San Martn - CONICET|http://www.iib.unsam.edu.ar/|Maintains
			World Health Organization, Special Programme for Research and Training in Tropical Diseases (WHO/TDR)|https://who.int/tdr|Funds
			Agencia Nacional de Promocin Cientfica (ANPCyT, Argentina)|https://www.argentina.gob.ar/ciencia/agencia|Funds
		Added:
			University of Washington, USA|https://www.washington.edu/|Undefined
			Instituto de Investigaciones Biotecnolgicas, Universidad de San Martn - CONICET|http://www.iib.unsam.edu.ar/|Maintains
			World Health Organization, Special Programme for Research and Training in Tropical Diseases (WHO/TDR)|https://who.int/tdr|Funds
			Agencia Nacional de Promocin Cientfica (ANPCyT, Argentina)|https://www.argentina.gob.ar/ciencia/agencia|Funds
		Removed:
			University of Washington, USA|https://www.washington.edu/|Maintains

	'standardsImplemented' has been modified:
		Before:
			Portable Network Graphics
		After:
			Portable Network Graphics
			Hyper Text Markup Language
		Added:
			Hyper Text Markup Language
		Removed:

	'supportLinks' has been modified:
		Before:
			FAQ|http://tdrtargets.org/faq
			email|tdr-targetgroup@sanger.ac.uk
			online documentation|http://tdrtargets.org/documentation
			wikipedia|https://en.wikipedia.org/wiki/TDR_Targets
		After:
			FAQ|http://tdrtargets.org/faq
			email|info@tdrtargets.org
			online documentation|http://tdrtargets.org/documentation
			wikipedia|https://en.wikipedia.org/wiki/TDR_Targets
		Added:
			email|info@tdrtargets.org
		Removed:
			email|tdr-targetgroup@sanger.ac.uk

	'description' has been modified:
		Before: Identification and ranking of targets against neglected tropical diseases
		After: Identification and ranking of targets and bioactive compounds against neglected tropical diseases. TDR Targets integrates chemical and genomic information and allows users to prioritize targets and compounds to develop and repurpose new drugs and chemical tools for human pathogens. 

The TDR Target Project was started in 2005 after a call for applications was launched by TDR (Special Programme for Research and Training in Tropical Diseases (UNICEF / UNDP / World Bank / WHO, http://www.who.int/tdr)). As a result, the TDR Targets Database was established to help develop a portfolio of candidate drug targets for 5 major human pathogens. This shortly turned into a resource for prioritizing targets for neglected tropical diseases. TDR Targets is led and run by the Trypanosomatics group at IIB-UNSAM (Argentina, https://trypanosomatics.org) with help with external collaborators worldwide.


	'countries' has been modified:
		Before:
			United Kingdom
		After:
			Argentina
		Added:
			Argentina
		Removed:
			United Kingdom

	'onto_domains' has been modified:
		Before:
			Annotation
			DNA sequence
			EC number
			GO-term enrichment report
			Gene expression data
			Gene name
			Genome annotation
			Pathway or network prediction
			Sequence length
			acceptor
			antigen
			bioactivity assay
			chemical descriptor
			disease
			donor
			gene
			glycosylphosphatidylinositol anchor
			logP descriptor
			molecular weight
			proton
			signal_peptide
			structure
		After:
			Annotation
			DNA sequence
			EC number
			GO-term enrichment report
			Gene expression data
			Gene name
			Genome annotation
			Pathway or network prediction
			Sequence length
			acceptor
			antigen
			bioactivity assay
			chemical descriptor
			chemical entity
			disease
			donor
			gene
			glycosylphosphatidylinositol anchor
			logP descriptor
			molecular weight
			proton
			signal_peptide
			structure
		Added:
			chemical entity
		Removed:

	'grants' has been modified:
		Before:
		After:
			A50830|
			PICT-2010-1479
			PICT-Glaxo-2013-0067
		Added:
			A50830|
			PICT-2010-1479
			PICT-Glaxo-2013-0067
		Removed:

	'miriam_id' has been modified:
		Before: None
		After: 

	'taxonomies' has been modified:
		Before:
			Brugia malayi
			Leishmania major
			Schistosoma mansoni
			Toxoplasma gondii
		After:
			Brugia malayi
			Chlamydia trachomatis
			Echinococcus granulosus
			Echinococcus multilocularis
			Entamoeba histolytica
			Giardia lamblia
			Leishmania major
			Loa Loa
			Mycobacterium leprae
			Mycobacterium tuberculosis
			Mycobacterium ulcerans
			Onchocerca volvulus
			Plasmodium falciparum
			Plasmodium vivax
			Schistosoma mansoni
			Toxoplasma gondii
			Treponema pallidum
			Trichomonas vaginalis
			Trypanosoma brucei
			Trypanosoma cruzi
			Wolbachia (Brugia malayi)
		Added:
			Chlamydia trachomatis
			Echinococcus granulosus
			Echinococcus multilocularis
			Entamoeba histolytica
			Giardia lamblia
			Loa Loa
			Mycobacterium leprae
			Mycobacterium tuberculosis
			Mycobacterium ulcerans
			Onchocerca volvulus
			Plasmodium falciparum
			Plasmodium vivax
			Treponema pallidum
			Trichomonas vaginalis
			Trypanosoma brucei
			Trypanosoma cruzi
			Wolbachia (Brugia malayi)
		Removed:

	'homepage' has been modified:
		Before: http://tdrtargets.org
		After: https://tdrtargets.org

	'contactORCID' has been modified:
		Before: 
		After: 0000-0003-1331-5741

            

Edits to 'https://fairsharing.org/FAIRsharing.6c4fvf' by 'The FAIRsharing Team' at 10:57, 21 Nov 2018 (approved):

	'domains' has been modified:
		Before:
			Acceptor
			Annotation
			Antigen
			Atomic composition
			Bioactivity
			Chemical descriptor
			Disease
			Donor
			Drug-like compound
			Enzyme Commission (EC) number
			Gene
			Gene Ontology (GO) enrichment
			Gene expression data
			Gene name
			Genome annotation
			Glycosylphosphatidylinositol (GPI) anchor
			Life Science
			Molecular weight
			Number of flexible bonds
			Pathway or network prediction
			Proton
			Rule of five compliance
			Sequence length
			Signal peptide
			Structure
			logP
		After:
			Acceptor
			Annotation
			Antigen
			Atomic composition
			Bioactivity
			Chemical descriptor
			DNA sequence data
			Disease
			Donor
			Drug-like compound
			Enzyme Commission (EC) number
			Gene
			Gene Ontology (GO) enrichment
			Gene expression data
			Gene name
			Genome annotation
			Glycosylphosphatidylinositol (GPI) anchor
			Life Science
			Molecular weight
			Number of flexible bonds
			Pathway or network prediction
			Proton
			Rule of five compliance
			Sequence length
			Signal peptide
			Structure
			logP
		Added:
			DNA sequence data
		Removed:

            

Edits to 'https://fairsharing.org/FAIRsharing.6c4fvf' by 'The FAIRsharing Team' at 18:49, 26 Sep 2016 (approved):

	'contactName' has been modified:
		Before:
			
		After:
			Fernn Agero
		Added:
		Removed: