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ready MACiE

General Information
MACiE is an electronic database of well-characterised enzymatic reactions. MACiE is the result of more than three years' collaboration between the Mitchell and Murray-Rust groups in the Unilever Centre and Prof. Janet Thornton at the European Bioinformatics Institute. The database contains the reaction mechanisms for 100 individual enzymes; this includes the overall reactions and the multiple steps that constitute them.

How to cite this record: MACiE; MACiE; DOI:; Last edited: Feb. 22, 2018, 2:49 p.m.; Last accessed: Mar 19 2018 5:02 a.m.

Record updated: Jan. 11, 2018, 11:54 a.m. by The FAIRsharing Team.


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MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms.

Holliday GL., Almonacid DE., Bartlett GJ., O'Boyle NM., Torrance JW., Murray-Rust P., Mitchell JB., Thornton JM.,
Nucleic Acids Res. 2007

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Grant Number(s)

  • BB/C51320X/1 (Biotechnology and Biological Sciences Research Council (BBSRC), UK)