databases > DOI:10.25504/FAIRsharing.tf6kj8

ready Reactome - a curated knowledgebase of biological pathways

Abbreviation:Reactome

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General Information
The cornerstone of Reactome is a freely available, open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes, vaccines, anti-cancer therapeutics and small molecules) participating in reactions form a network of biological interactions and are grouped into pathways. Examples of biological pathways in Reactome include classical intermediary metabolism, signaling, transcriptional regulation, apoptosis and disease. Inferred orthologous reactions are available for 15 non-human species including mouse, rat, chicken, zebrafish, worm, fly, and yeast.


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How to cite this record FAIRsharing.org: Reactome; Reactome - a curated knowledgebase of biological pathways; DOI: https://doi.org/10.25504/FAIRsharing.tf6kj8; Last edited: March 12, 2021, 10:46 a.m.; Last accessed: Apr 17 2021 6:12 a.m.

Publication for citation  The reactome pathway knowledgebase. Jassal B,Matthews L,Viteri G,Gong C,Lorente P,Fabregat A,Sidiropoulos K,Cook J,Gillespie M,Haw R,Loney F,May B,Milacic M,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P; Nucleic Acids Res ; 2019; 10.1093/nar/gkz1031;


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Record updated: March 11, 2021, 4:48 p.m. by The FAIRsharing Team.

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Pathway visualization in the Reactome pathway database

Reactome






Publications

Reactome: a knowledgebase of biological pathways.

Joshi-Tope G., Gillespie M., Vastrik I., D'Eustachio P., Schmidt E., de Bono B., Jassal B., Gopinath GR., Wu GR., Matthews L., Lewis S., Birney E., Stein L.,
Nucleic Acids Res. 2005

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The Reactome Pathway Knowledgebase.

Fabregat A,Jupe S,Matthews L,Sidiropoulos K,Gillespie M,Garapati P,Haw R,Jassal B,Korninger F,May B,Milacic M,Roca CD,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Viteri G,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P
Nucleic Acids Res 2017

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The reactome pathway knowledgebase.

Jassal B,Matthews L,Viteri G,Gong C,Lorente P,Fabregat A,Sidiropoulos K,Cook J,Gillespie M,Haw R,Loney F,May B,Milacic M,Rothfels K,Sevilla C,Shamovsky V,Shorser S,Varusai T,Weiser J,Wu G,Stein L,Hermjakob H,D'Eustachio P
Nucleic Acids Res 2019

View Paper (PubMed) View Publication