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ready UniProt Knowledgebase


General Information
The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation. In addition to capturing the core data mandatory for each UniProtKB entry (mainly, the amino acid sequence, protein name or description, taxonomic data and citation information), as much annotation information as possible is added. This includes widely accepted biological ontologies, classifications and cross-references, and clear indications of the quality of annotation in the form of evidence attribution of experimental and computational data. The UniProt Knowledgebase consists of two sections: a reviewed section containing manually-annotated records with information extracted from literature and curator-evaluated computational analysis (aka "UniProtKB/Swiss-Prot"), and an unreviewed section with computationally analyzed records that await full manual annotation (aka "UniProtKB/TrEMBL").

How to cite this record ; DOI: 10.25504/FAIRsharing.s1ne3g; Last edited: Feb. 22, 2018, 2:56 p.m.; Last accessed: Feb 22 2018 10:46 p.m.

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This record is maintained by uniprot

Record updated: March 30, 2017, 11:42 a.m. by The FAIRsharing Team.



Additional Information


UniProt: a hub for protein information

The UniProt Consortium
Nucleic Acids Res. 2015

View Paper (PubMed) View Paper (DOI)

Implementing Policies


Record Maintainer

  • This record is maintained by uniprot



Grant Number(s)

  • DBI-1062520 (National Science Foundation)

  • G-1307 (Parkinson's Disease United Kingdom (PDUK))

  • G08LM010720 (US National Institutes of Health (NIH))

  • P20GM103446 (US National Institutes of Health (NIH))

  • R01GM080646 (US National Institutes of Health (NIH))

  • RG/13/5/30112 (British Heart Foundation)

  • U41HG007822 (US National Institutes of Health (NIH))

  • U41HG02273 (US National Institutes of Health (NIH))