Databases > DOI:10.25504/FAIRsharing.xgcyyn

ready CATH Protein Structure Classification

Abbreviation:CATH domain

General Information
The CATH database is a hierarchical domain classification of protein structures in the Protein Data Bank. Protein structures are classified using a combination of automated and manual procedures. There are four major levels in this hierarchy; Class (secondary structure classification, e.g. mostly alpha), Architecture (classification based on overall shape), Topology (fold family) and Homologous superfamily (protein domains which are thought to share a common ancestor). This collection is concerned with superfamily classification.

How to cite this record: CATH domain; CATH Protein Structure Classification; DOI:; Last edited: Feb. 22, 2018, 2:56 p.m.; Last accessed: Mar 19 2018 4:58 a.m.

Record updated: Sept. 7, 2016, 6:06 p.m. by The FAIRsharing Team.



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CATH--a hierarchic classification of protein domain structures.

Orengo CA., Michie AD., Jones S., Jones DT., Swindells MB., Thornton JM.,
Structure 1997

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Functional classification of CATH superfamilies: a domain-based approach for protein function annotation.

Das S,Lee D,Sillitoe I,Dawson NL,Lees JG,Orengo CA
Bioinformatics 2016

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The history of the CATH structural classification of protein domains.

Sillitoe I,Dawson N,Thornton J,Orengo C
Biochimie 2015

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CATH: comprehensive structural and functional annotations for genome sequences.

Sillitoe I,Lewis TE,Cuff A,Das S,Ashford P,Dawson NL,Furnham N,Laskowski RA,Lee D,Lees JG,Lehtinen S,Studer RA,Thornton J,Orengo CA
Nucleic Acids Res 2014

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The CATH protein family database: a resource for structural and functional annotation of genomes.

Orengo CA,Bray JE,Buchan DW,Harrison A,Lee D,Pearl FM,Sillitoe I,Todd AE,Thornton JM
Proteomics 2002

View Paper (PubMed)