CATH Protein Structure Classification

Abbreviation:CATH domain

General Information

The CATH database is a hierarchical domain classification of protein structures in the Protein Data Bank. Protein structures are classified using a combination of automated and manual procedures. There are four major levels in this hierarchy; Class (secondary structure classification, e.g. mostly alpha), Architecture (classification based on overall shape), Topology (fold family) and Homologous superfamily (protein domains which are thought to share a common ancestor). This collection is concerned with superfamily classification.

Homepage http://www.cathdb.info/

Developed in United Kingdom

Created in 1996

Taxonomic range

Scope and data types

How to cite this record FAIRsharing.org: CATH domain; CATH Protein Structure Classification; DOI: https://doi.org/10.25504/FAIRsharing.xgcyyn; Last edited: Aug. 22, 2018, 1:53 p.m.; Last accessed: Sep 25 2018 6:25 a.m.

Record updated: July 30, 2018, 6:22 p.m. by The FAIRsharing Team.

Show edit history

Edits to 'https://fairsharing.org/FAIRsharing.xgcyyn' by 'The FAIRsharing Team' at 18:22, 30 Jul 2018 (approved):

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			blog|http://orengogroup.info/
			email|cathteam@biochem.ucl.ac.uk
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			help|http://www.cathdb.info/wiki
			twitter|@CATHDatabase
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			FAQ|http://www.cathdb.info/wiki/doku/?id=faq
			blog|http://orengogroup.info/
			email|cathteam@biochem.ucl.ac.uk
			forum|http://orengogroup.info/
			help|http://www.cathdb.info/wiki
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			cath-tools||https://github.com/UCLOrengoGroup/cath-tools
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			MAFFT||https://mafft.cbrc.jp/alignment/software/
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			cath-tools||https://github.com/UCLOrengoGroup/cath-tools
			BLAST||https://blast.ncbi.nlm.nih.gov/Blast.cgi
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			MAFFT||https://mafft.cbrc.jp/alignment/software/
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Edits to 'https://fairsharing.org/FAIRsharing.xgcyyn' by 'The FAIRsharing Team' at 18:06, 07 Sep 2016 (approved):

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Support

General

FAQ	FAQ
blog	http://orengogroup.info/
support email	cathteam@biochem.ucl.ac.uk
forum	http://orengogroup.info/
help	http://www.cathdb.info/wiki
twitter	@CATHDatabase

Additional Information

Contact	Ian Sillitoe
Identifiers.org	MIR:00000210

Tools

cath-tools	https://github.com/UCLOrengoGroup/cath-tools
BLAST	https://blast.ncbi.nlm.nih.gov/Blast.cgi
HUMMER	http://hmmer.org
MAFFT	https://mafft.cbrc.jp/alignment/software/
Scorecons	https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/valdar/scorecons_ ...

Access / Retrieve Data

Conditions of Use

Applies to: Data use

Attribution required
Publicly available data
CATH Privacy Policy

Data Access

Download	http://www.cathdb.info/download
Browse	http://www.cathdb.info/browse/tree
Search	http://www.cathdb.info/search

Publications

CATH--a hierarchic classification of protein domain structures.

Orengo CA., Michie AD., Jones S., Jones DT., Swindells MB., Thornton JM.,
Structure 1997

View Paper (PubMed)

Functional classification of CATH superfamilies: a domain-based approach for protein function annotation.

Das S,Lee D,Sillitoe I,Dawson NL,Lees JG,Orengo CA
Bioinformatics 2016

View Paper (PubMed) View Publication

The history of the CATH structural classification of protein domains.

Sillitoe I,Dawson N,Thornton J,Orengo C
Biochimie 2015

View Paper (PubMed) View Publication

CATH: comprehensive structural and functional annotations for genome sequences.

Sillitoe I,Lewis TE,Cuff A,Das S,Ashford P,Dawson NL,Furnham N,Laskowski RA,Lee D,Lees JG,Lehtinen S,Studer RA,Thornton J,Orengo CA
Nucleic Acids Res 2014

View Paper (PubMed) View Publication

The CATH protein family database: a resource for structural and functional annotation of genomes.

Orengo CA,Bray JE,Buchan DW,Harrison A,Lee D,Pearl FM,Sillitoe I,Todd AE,Thornton JM
Proteomics 2002

View Paper (PubMed)

Related Standards

Reporting Guidelines

No guidelines defined

Terminology Artifacts

Gene Ontology

Models and Formats

Related Databases

Implementing Policies

This record is not implemented by any policy.

Credit

Record Maintainer

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Funds

Biotechnology and Biological Sciences Research Council (BBSRC), UK (Government body)
European Research Council, Brussels, Belgium (Government body)
Medical Research Council (Government body)
National Institutes of Health (Government body)
The Wellcome Trust, UK (Research institute)
The Wellcome Trust (Research institute)

Maintains

University College London (University)

Grant Number(s)

081989/Z/07/Z (The Wellcome Trust)
BB/K020013/1 (Biotechnology and Biological Sciences Research Council (BBSRC), UK)

CATH Protein Structure Classification

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