Databases > DOI:10.25504/FAIRsharing.gg60g3

ready The Improved Database Of Chimeric Transcripts and RNA-Seq Data

Abbreviation:ChiTaRS

General Information
The ESTs and mRNAs from GenBank have been used to identify chimeric RNAs of two or more different genes. By analyzing thousands of chimeric ESTs by RNA sequencing, we found that the expression level of chimeric ESTs is generally low and they are highly tissue specific in normal cells. Here we present the improved version of the ChiTaRS database (ChiTaRS-3.1) of about 40,000 chimeric transcripts in humans, mice, fruit flies, zebrafishes, cows, rats, pig and yeast. In the current version we extended the experimental data evidence as well as included a novel type of the sense-antisense chimeric transcripts of the same gene confirmed experimentally by RT-PCR, qPCR, RNA-sequencing and mass-spec peptides. In addition, we collected about 11,700 human cancer breakpoints with the expression levels of chimeric RNAs confirmed by the paired-end RNA-sequencing experiments in different tissues in humans, mice and fruit flies.




How to cite this record FAIRsharing.org: ChiTaRS; The Improved Database Of Chimeric Transcripts and RNA-Seq Data; DOI: 10.25504/FAIRsharing.gg60g3; Last edited: Feb. 22, 2018, 2:57 p.m.; Last accessed: Jul 17 2018 12:15 p.m.


This record is maintained by AlessandroGorohovski  ORCID

Record updated: Nov. 23, 2017, 1:43 p.m. by The FAIRsharing Team.


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ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

Milana Frenkel-Morgenstern1, Alessandro Gorohovski, Vincent Lacroix, Mark Rogers, Kristina Ibanez, Cesar Boullosa, Eduardo Andres Leon, Asa Ben-Hur and Alfonso Valencia
Nucleic Acids Research 2012

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ChiTaRS 2.1--an improved database of the chimeric transcripts and RNA-seq data with novel sense-antisense chimeric RNA transcripts.

Frenkel-Morgenstern M,Gorohovski A,Vucenovic D,Maestre L,Valencia A
Nucleic Acids Res 2014

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ChiTaRS-3.1-the enhanced chimeric transcripts and RNA-seq database matched with protein-protein interactions.

Gorohovski A,Tagore S,Palande V,Malka A,Raviv-Shay D,Frenkel-Morgenstern M
Nucleic Acids Res 2016

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