Record added: Nov. 3, 2015, 9:44 a.m.
Record updated: Jan. 6, 2017, 2:59 p.m. by The FAIRsharing Team.

Edits to 'https://fairsharing.org/FAIRsharing.x7pwnw' by 'The FAIRsharing Team' at 17:38, 19 Jul 2018 (approved):

	'description' has been modified:
		Before: With the advent of ribosome profiling, a next generation sequencing technique providing a snap-shot of translated mRNA in a cell, many short open reading frames (sORFs) with were identified. Follow-up studies revealed the existence of functional peptides, so-called micropeptides, translated from these sORFs, indicating a new class of bio-active peptides. Over the last few years, several micropeptides exhibiting important cellular functions were discovered. However, ribosome occupancy does not necessarily imply an actual function of the translated peptide, leading to the development of various tools assessing the coding potential of sORFs. Here, we introduce sORFs.org (http://www.sorfs.org), a novel database for sORFs identified using ribosome profiling. Starting from ribosome profiling, sORFs.org identifies sORFs, incorporates state-of-the-art tools and metrics and stores results in a public database. Two query interfaces are provided, a default one enabling quick lookup of sORFs and a BioMart interface providing advanced query and export possibilities. At present, sORFs.org harbors 263 354 sORFs that demonstrate ribosome occupancy, originating from three different cell lines: HCT116 (human), E14_mESC (mouse) and S2 (fruit fly). sORFs.org aims to provide an extensive sORFs database accessible to researchers with limited bioinformatics knowledge, thus enabling easy integration into personal projects. 
		After: sORFs.org is a database for sORFs identified using ribosome profiling. Starting from ribosome profiling, sORFs.org identifies sORFs, incorporates state-of-the-art tools and metrics and stores results in a public database. Two query interfaces are provided, a default one enabling quick lookup of sORFs and a BioMart interface providing advanced query and export possibilities. At present, sORFs.org harbors 263 354 sORFs that demonstrate ribosome occupancy, originating from three different cell lines: HCT116 (human), E14_mESC (mouse) and S2 (fruit fly).  Domain list has changed:  Previous values: Genome maps|| Life Science|domain| New values:  Genome maps|| Life Science|domain| Ribosomal RNA|| Publication List has changed:  Previous values: sORFs.org: a repository of small ORFs identified by ribosome profiling New values:  sORFs.org: a repository of small ORFs identified by ribosome profiling. Data processes have changed:  Previous values: defaullt query interface BioMart query interface New values:  search BioMart query interface submit Organisations have changed:  Previous values: BioBix FWO-vlaanderen New values:  Lab of bioinformatics and computational genomics (BioBix)|Belgium FWO-vlaanderen|Belgium Related databases have changed:  Previous values: New values:  biodbcore-000107: UCSC Genome Browser database Grants have changed:  Previous values: G0D3114N New values:  12A7813N G0D3114N