databases > DOI:10.25504/FAIRsharing.e5y0j0

ready Clinical Knowledgebase

Abbreviation:JAX-CKB

General Information
The Jackson Laboratory Clinical Knowledgebase (CKB) is a semi-automated/manually curated database of gene/variant annotations, therapy knowledge, diagnostic/prognostic information, and clinical trials related to oncology. CKB not only contains current information on the protein effect of somatic gene variants, but also connects the variant to targeted therapies through an efficacy evidence annotation. In addition, CKB captures clinical trial patient eligibility criteria that include genomic alterations (genotype-specific). The public access version of CKB encompasses 82 commonly known driver genes. Users can search CKB via gene, gene variants, drug, drug class, indication, and clinical trials. The web-based version of CKB is designed to interrogate the knowledgebase for specific data attributes while also enabling a robust browse like feature when the desired content is unknown.

Homepage https://jax.org/ckb

Countries that developed this resource United States

Created in 2014

Taxonomic range





How to cite this record FAIRsharing.org: JAX-CKB; Clinical Knowledgebase; DOI: https://doi.org/10.25504/FAIRsharing.e5y0j0; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Nov 25 2020 12:13 a.m.


This record is maintained by smockus  ORCID

Record added: June 14, 2016, 10:37 a.m.
Record updated: Oct. 1, 2018, 12:09 p.m. by smockus.

Show edit history


In Collections
RDA Covid-19 WG Resources

Support

General

support email ckbsupport@jax.org

Additional Information

Contact Susan Mockus   ORCID

Tools

    No tools defined


Access / Retrieve Data

Conditions of Use





Publications

The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies.

Patterson SE1, Liu R2, Statz CM3, Durkin D4, Lakshminarayana A5, Mockus SM6.
Hum Genomics 2016

View Paper (PubMed) View Publication

Related Standards

Reporting Guidelines

No guidelines defined

Terminology Artifacts

Models and Formats

No syntax standards defined

Identifier Schemas

No identifier schema standards defined

Metrics

No metrics standards defined


Related Databases

Implementing Policies

This record is not implemented by any policy.


Credit

Record Maintainer

Maintains