databases > DOI:10.25504/FAIRsharing.68f4xz

ready mirDNMR

General Information
mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.

Homepage https://www.wzgenomics.cn/mirdnmr/

Developed in China

Created in 2016

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How to cite this record FAIRsharing.org: mirDNMR; mirDNMR; DOI: https://doi.org/10.25504/FAIRsharing.68f4xz; Last edited: Jan. 8, 2019, 1:23 p.m.; Last accessed: Feb 16 2019 5:57 a.m.


This record is maintained by YiJiang

Record added: Nov. 3, 2016, 12:12 p.m.
Record updated: Nov. 8, 2016, 9:01 p.m. by The FAIRsharing Team.

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Access / Retrieve Data

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Data Access

Browse https://www.wzgenomics.cn/mirdnmr/tableDNMR.php
Download data https://www.wzgenomics.cn/mirdnmr/download.php



Publications

mirDNMR: a gene-centered database of background de novo mutation rates in human.

Jiang Y,Li Z,Liu Z,Chen D,Wu W,Du Y,Ji L,Jin ZB,Li W,Wu J
Nucleic Acids Res 2016

View Paper (PubMed) View Publication

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  • This record is maintained by YiJiang

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