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Databases > biodbcore-000843

ready Target Central Resource Database

Abbreviation:TCRD

General Information
TCRD is the central resource behind the Illuminating the Druggable Genome Knowledge Management Center (IDG-KMC). TCRD contains information about human targets, with special emphasis on four families of targets that are central to the NIH IDG initiative: GPCRs, kinases, ion channels and nuclear receptors. Olfactory GPCRs (oGPCRs) are treated as a separate family. A key aim of the KMC is to classify the development/druggability level of targets. The official public portal for TCRD is Pharos (pharos.nih.gov). Based on modern web design principles the Pharos interface provides facile access to all data types collected by the KMC. Given the complexity of the data surrounding any target, efficient and intuitive visualization has been a high priority, to enable users to quickly navigate & summarize search results and rapidly identify patterns. A critical feature of the interface is the ability to perform flexible search and subsequent drill down of search results. Underlying the interface is a RESTful API that provides programmatic access to all KMC data, allowing for easy consumption in user applications.



This record is maintained by Tudorzinho  and rguha

Record added: Nov. 4, 2016, 5:29 p.m.
Record updated: June 8, 2017, 12:43 p.m. by The FAIRsharing Team.


Support

General

Additional Information


Tools

Access / Retrieve Data

Conditions of Use

Applies to: Data use


REST Web Services



Connectivity
Related Standards


Implementing Policies

This record is not implemented by any policy.



Publications

Pharos: Collating protein information to shed light on the druggable genome.

Nguyen DT,Mathias S,Bologa C,Brunak S,Fernandez N,Gaulton A,Hersey A,Holmes J,Jensen LJ,Karlsson A,Liu G,Ma'ayan A,Mandava G,Mani S,Mehta S,Overington J,Patel J,Rouillard AD,Schurer S,Sheils T,Simeonov A,Sklar LA,Southall N,Ursu O,Vidovic D,Waller A,Yang J,Jadhav A,Oprea TI,Guha R
Nucleic Acids Res 2016

View Paper (PubMed) View Paper (DOI)