ready Reframedb

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Reframedb is a comprehensive open-access, drug repositioning screening set of 12,000 compounds that was assembled by combining three widely-used commercial drug competitive intelligence databases (Clarivate Integrity, GVK Excelra GoStar and Citeline Pharmaprojects), together with extensive patent mining of small molecules that have been dosed in humans. To date ~12,000 compounds (~80% of compounds identified from data mining) have been purchased or synthesized, and subsequently plated for screening.


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Record added: May 26, 2020, 3:19 p.m.
Record updated: Oct. 5, 2020, 4:18 p.m. by The FAIRsharing Team.

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The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis.

Janes J,Young ME,Chen E,Rogers NH,Burgstaller-Muehlbacher S,Hughes LD,Love MS,Hull MV,Kuhen KL,Woods AK,Joseph SB,Petrassi HM,McNamara CW,Tremblay MS,Su AI,Schultz PG,Chatterjee AK
Proc Natl Acad Sci U S A 2018

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