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Standards > terminology artifact > bsg-s000129


ready Mammalian Phenotype Ontology

Abbreviation:MP


General Information
The observable morphological, physiological, behavioral and other characteristics of mammalian organisms that are manifested through development and lifespan.


Collected/Recommended By



This record is maintained by csmithjax  ORCID  and jberghout  ORCID

Record updated: May 26, 2017, 9:25 a.m. by The FAIRsharing Team.




Tools

Schemas

No XSD schemas defined


Access / Retrieve Data

Conditions of Use

Applies to: Data use

Data Access


REST Web Services



Connectivity
MP Ontology Display

View in BioPortal.


Disclaimer: This widget assumes the availability of the ontology resources in the NCBO BioPortal.

View in OBO Foundry.



Related Standards

Terminology Artifacts

No semantic standards defined

Models and Formats

No syntax standards defined


Implementing Databases (8)
Mouse Phenome Database
Characterizations of hundreds of strains of laboratory mice to facilitate translational discoveries and to assist in selection of strains for experimental studies. Data sets are voluntarily contributed by researchers or retrieved by us from public sources. MPD has three major types of strain-centric data sets: phenotype strain surveys, SNP and variation data, and gene expression strain surveys.

neXtProt
neXtProt is a comprehensive human-centric discovery platform, offering its users a seamless integration of and navigation through protein-related data.

Rat Genome Database
The Rat Genome Database is the premier site for genetic, genomic, phenotype, and disease data generated from rat research. It provides easy access to corresponding human and mouse data for cross-species comparison and its comprehensive data and innovative software tools make it a valuable resource for researchers worldwide.

Mouse Genome Database - a Mouse Genome Informatics (MGI) Resource
MGI is the international database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data to facilitate the study of human health and disease. Data includes gene characterization, nomenclature, mapping, gene homologies among mammals, sequence links, phenotypes, allelic variants and mutants, and strain data.

MouseMine @ MGI
A database of integrated mouse data from MGI, powered by InterMine. MouseMine is member of InterMOD, a consortium of model organism databases dedicated to making cross-species data analysis easier through ongoing coordination and collaborative system development.

GeneWeaver
The GeneWeaver data and analytics website is a publically available resource for storing, curating and analyzing sets of genes from heterogeneous data sources. The system enables discovery of relationships among genes, variants, traits, drugs, environments, anatomical structures and diseases implicitly found through gene set intersections. By enumerating the common and distinct biological molecules associated with all subsets of curated or user submitted groups of gene sets and gene networks, GeneWeaver empowers users with the ability to construct data driven descriptions of shared and unique biological processes, diseases and traits within and across species.

Deciphering the Mechanisms of Developmental Disorders
Initiated in 2013, DMDD has the ambitious goal of identifying all embryonic lethal knockout lines made at the Wellcome Trust Sanger institute, through their work as a major centre for creation of individual mouse gene knockouts. DMDD uses a combination of comprehensive 3D imaging, tissue histology, immunocytochemistry and transcriptomics to identify abnormalities in embryo and placental structure for each embryonic lethal line. All data is made freely available via this web site, enabling individual researchers to identify lines relevant to their own research. The DMDD programme is coordinating its work with similar international efforts through the umbrella of the International Mouse Phenotyping Consortium.

Open Targets
Open Targets designed and developed an integration and visualization platform that provides evidence about the association of known and potential drug targets with diseases. The platform is designed to support identification and prioritization of biological targets for follow-up. Each drug target is linked to a disease using integrated genome-wide data from a broad range of data sources. The platform provides either a target-centric workflow to identify diseases that may be associated with a specific target, or a disease-centric workflow to identify targets that may be associated with a specific disease. Users can easily transition between these target- and disease-centric workflows.

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Implementing Policies

This record is not implemented by any policy.


Credit

Record Maintainer

Funds

Maintains

Grant Number(s)

  • HG000330 (National Human Genome Research Institute)


Publications

The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information.

Smith CL,Goldsmith CA,Eppig JT
Genome Biol 2005

View Paper (PubMed) View Paper (DOI)

The mammalian phenotype ontology: enabling robust annotation and comparative analysis.

Smith CL,Eppig JT
Wiley Interdiscip Rev Syst Biol Med 2010

View Paper (PubMed) View Paper (DOI)

The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data.

Smith CL,Eppig JT
Mamm Genome 2012

View Paper (PubMed) View Paper (DOI)

Expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens.

Smith CL,Eppig JT
J Biomed Semantics 2015

View Paper (PubMed) View Paper (DOI)