Standards > reporting guideline > bsg-s000523


ready Minimum Information Required for A Glycomics Experiment - Mass Spectrometric Analysis

Abbreviation:MIRAGE MS


General Information
MIRAGE (Minimum Information Required for A Glycomics Experiment) was created to improve the quality of glycomics data in the scientific literature. Researchers seeking to understand the biochemical structure–function relationships of carbohydrates require detailed descriptions of the assay conditions and the experimental results. Currently, these data are insufficiently reported in the literature. A basic description on the sample preparation workflow is required. In contrast to proteomics, different types of glycoconjugates require partially different release approaches, which in turn can have direct influence on the following conditions/parameters: released glycans or still attached to protein/lipid; type of glycan (N-glycan, O-glycan, proteoglycan fragment); and sample pre-treatment prior MS-Analyses (non, reduced, permethylated, endo/exoglycosidase digested, fluorescent label, online/offline LC-separation).



This record is maintained by CKettner  ORCID

Record updated: Feb. 14, 2017, 11:12 a.m. by The FAIRsharing Team.


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Implementing Databases (1)
UniCarbKB
UniCarbKB is an initiative that aims to promote the creation of an online information storage and search platform for glycomics and glycobiology research. The knowledgebase will offer a freely accessible and information-rich resource supported by querying interfaces, annotation technologies and the adoption of common standards to integrate structural, experimental and functional data.

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Publications

The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting mass-spectrometry-based glycoanalytic data

Kolarich D, Rapp E, Struwe WB, Haslam SM, Zaia J, McBride R, Agravat S, Campbell MP, Kato M, Ranzinger R, Kettner C, York WS
Mol Cell Proteomics 2012

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MIRAGE: The minimum information required for a glycomics experiment

York WS, Agravat S, Aoki-Kinoshita KF, McBride R, Campbell MP, Costello CE, Dell A, Feizi T, Haslam SM, Karlsson N, Khoo K-H, Kolarich D, Liu Y, Novotny M, Packer NH, Paulson JC, Rapp E, Ranzinger R, Rudd PM, Smith DF, Struwe WB, Tiemeyer M, Wells L, Zaia J, and Kettner C
Glycobiology 2014

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The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets.

Struwe WB,Agravat S,Aoki-Kinoshita KF,Campbell MP,Costello CE,Dell A,Ten Feizi,Haslam SM,Karlsson NG,Khoo KH,Kolarich D,Liu Y,McBride R,Novotny MV,Packer NH,Paulson JC,Rapp E,Ranzinger R,Rudd PM,Smith DF,Tiemeyer M,Wells L,York WS,Zaia J,Kettner C
Glycobiology 2016

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