standards > model/format > DOI:10.25504/FAIRsharing.pDq8lX


ready Hierarchical Editing Language for Macromolecules

Abbreviation: HELM


General Information
HELM (Hierarchical Editing Language for Macromolecules) enables the representation of a wide range of biomolecules (e.g. proteins, nucleotides, antibody drug conjugates) whose size and complexity render existing small-molecule and sequence-based informatics methodologies impractical or unusable. HELM solves this problem through a hierarchical notation that represents complex macromolecules as polymeric structures with support for unnatural components (e.g. unnatural amino acids) and chemical modifications.



How to cite this record FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Dec 06 2019 8:18 a.m.


This record is maintained by HELMInfo  (MacroMol)

Record added: July 18, 2018, 4:44 p.m.
Record updated: July 19, 2018, 1:16 p.m. by The FAIRsharing Team.

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General

Additional Information



Schemas

No XSD schemas defined


Access / Retrieve Data

Conditions of Use

Applies to: Database software




Publications

HELM: a hierarchical notation language for complex biomolecule structure representation.

Zhang T,Li H,Xi H,Stanton RV,Rotstein SH
J Chem Inf Model 2012

View Paper (PubMed) View Publication

HELM Software for Biopolymers.

Milton J,Zhang T,Bellamy C,Swayze E,Hart C,Weisser M,Hecht S,Rotstein S
J Chem Inf Model 2017

View Paper (PubMed) View Publication

Related Standards

Reporting Guidelines

No guidelines defined

Terminology Artifacts

No semantic standards defined

Models and Formats

No syntax standards defined

Identifier Schemas

No identifier schema standards defined

Metrics

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Implementing Databases (1)
PubChem
PubChem is organized as three linked databases within the NCBI's Entrez information retrieval system. These are PubChem Substance, PubChem Compound, and PubChem BioAssay. PubChem also provides a fast chemical structure similarity search tool. More information about using each component database may be found using the links in the homepage.

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