standards > model/format > bsg-s001478

ready CRAM

General Information
CRAM is a sequencing read file format that is highly space efficient by using reference-based compression of sequence data and offers both lossless and lossy modes of compression. Building on early proof-of-principle for reference-based compression (Hsi-Yang Fritz, et al. (2011). Genome Res. 21:734-740), the CRAM format balances usability with compression efficiency.

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Record added: May 22, 2020, 3:11 p.m.
Record updated: May 22, 2020, 3:27 p.m. by The FAIRsharing Team.

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Efficient storage of high throughput DNA sequencing data using reference-based compression.

Hsi-Yang Fritz M,Leinonen R,Cochrane G,Birney E
Genome Res 2011

View Paper (PubMed) View Publication

The Scramble conversion tool.

Bonfield JK
Bioinformatics 2014

View Paper (PubMed) View Publication

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Related Databases (1)
The European Genome-phenome Archive
The European Genome-phenome Archive (EGA) allows you to explore datasets from genomic studies, provided by a range of data providers. Access to datasets must be approved by the specified Data Access Committee (DAC).

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Grant Number(s)

  • 085532 (The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK)

  • 098051 (The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK)