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LINCS Project

The LINCS project is based on the premise that disrupting any one of the many steps of a given biological process will cause related changes in the molecular and cellular characteristics, behavior, and/or function of the cell – the observable composite of which is known as the cellular phenotype. Observing how and when a cell’s phenotype is altered by specific stressors can provide clues about the underlying mechanisms involved in perturbation and ultimately, disease. In LINCS Production Phase II, the LINCS Data Working Group (DWG) is currently developing extended metadata specifications describing LINCS reagents, assays and experiments. Annotations for the perturbagens (small molecules, siRNA, growth factors and other ligands), cells, and some elements of experimental metadata should be common between all LINCS Centers. This will facilitate development of data analysis, formatting, and visualization strategies by LINCS investigators, and also the development of databases and data repositories in which to store and share LINCS data. This collection contains records for all LINCS resources associated with the project.

This record is maintained by: cchung ORCID

Record added: April 27, 2016, 2:24 p.m..
Record updated: Feb. 10, 2021, 9:53 a.m. by The FAIRsharing Team.

Homepage Reference

Taxonomic range

Homo sapiens

Knowledge Domains

Subjects

User-defined Tags

Chemogenomics

Metadata standardization

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Show edit history

Edits to 'https://fairsharing.org/bsg-c000018' by 'The FAIRsharing Team' at 11:55, 17 Jan 2017 (approved):

	'name' has been modified:
		Before: NIH LINCS
		After: NIH LINCS

Edits to 'https://fairsharing.org/bsg-c000018' by 'cchung' at 16:32, 07 Mar 2017 (approved):

	'name' has been modified:
		Before: LINCS Project
		After: LINCS Project

Edits to 'https://fairsharing.org/bsg-c000018' by 'The FAIRsharing Team' at 12:09, 01 Jun 2017 (approved):

	'reference_url' has been modified:
		Before: http://www.lincsproject.org/LINCS/data/standards
		After: http://www.lincsproject.org/LINCS/data/standards

Edits to 'https://fairsharing.org/bsg-c000018' by 'The FAIRsharing Team' at 09:53, 10 Feb 2021 (approved):

	'onto_domains' has been modified:
		Before:
			Experiment report
			chemical-disease association
			chemical-gene assocation
			chromatin structure variation
		After:
			chemical-disease association
			chemical-gene assocation
			chromatin structure variation
			protocol
		Added:
			protocol
		Removed:
			Experiment report

18 records in view

Name	Abbreviation	Type	Subject	Domain	Taxonomy	Related Database	Related Standard	Related Policy	In Collection/Recommendation
Library of Integrated Network-Based Cellular Signatures Data Portal	LINCS Data Portal	Database	Life Science	Gene expression data Cellular assay Molecular interaction Phenotype Small molecule	Homo sapiens	DataMed OmicsDI	CL OmicsDI XML format BAO OME-TIFF LINCS 1: Small Molecules Plus 16 more...	None	NIH-supported data repositories Open Science Prize LINCS Project RDA Covid-19 WG Resources
LINCS Extended Metadata Standard: Antibody Reagents	LINCS 2: Antibody Reagents	Standard	Life Science	Gene expression data Reaction data Catalytic activity Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 2: Small molecules LINCS 2: Embryonic Stem Cells LINCS 2: Primary Cells LINCS 2: Other Reagents LINCS 2: iPSCs Plus 4 more...	None	RDA Covid-19 WG Resources LINCS Project
LINCS Extended Metadata Standard: Cell lines	LINCS 2: Cell lines	Standard	Life Science	Gene expression data Reaction data Catalytic activity Cell line Cellular assay	Homo sapiens	LINCS Data Portal	MIACA LINCS 2: iPSCs LINCS 2: Differentiated Cells LINCS 2: Primary Cells LINCS 2: Small molecules Plus 5 more...	None	RDA Covid-19 WG Resources LINCS Project
LINCS Extended Metadata Standard: Differentiated Cells	LINCS 2: Differentiated Cells	Standard	Life Science	Gene expression data Reaction data Catalytic activity Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 2: Small molecules LINCS 2: Nucleic Acid Reagents LINCS 2: Embryonic Stem Cells LINCS 2: Primary Cells LINCS 2: Other Reagents Plus 4 more...	None	RDA Covid-19 WG Resources LINCS Project
LINCS Extended Metadata Standard: Embryonic Stem Cells	LINCS 2: Embryonic Stem Cells	Standard	Life Science	Cell line Cellular assay Stem cell	Homo sapiens	LINCS Data Portal	LINCS 2: Proteins LINCS 2: iPSCs LINCS 2: Other Reagents LINCS 2: Small molecules LINCS 2: Primary Cells Plus 4 more...	None	LINCS Project
LINCS Extended Metadata Standard: Induced Pluripotent Stem Cells	LINCS 2: iPSCs	Standard	Life Science	Gene expression data Reaction data Catalytic activity Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 2: Embryonic Stem Cells LINCS 2: Proteins LINCS 2: Small molecules LINCS 2: Other Reagents LINCS 2: Primary Cells Plus 4 more...	None	RDA Covid-19 WG Resources LINCS Project
LINCS Extended Metadata Standard: Nucleic Acid Reagents	LINCS 2: Nucleic Acid Reagents	Standard	Life Science	Reagent	Homo sapiens	LINCS Data Portal	LINCS 2: Small molecules LINCS 2: Primary Cells LINCS 2: iPSCs LINCS 2: Differentiated Cells LINCS 2: Proteins Plus 4 more...	None	LINCS Project
LINCS Extended Metadata Standard: Other Reagents	LINCS 2: Other Reagents	Standard	Life Science	Gene expression data Reaction data Catalytic activity Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 2: Embryonic Stem Cells LINCS 2: Small molecules LINCS 2: iPSCs LINCS 2: Proteins LINCS 2: Primary Cells Plus 4 more...	None	RDA Covid-19 WG Resources LINCS Project
LINCS Extended Metadata Standard: Primary Cells	LINCS 2: Primary Cells	Standard	Life Science	Gene expression data Reaction data Catalytic activity Cellular assay	Homo sapiens	LINCS Data Portal	MIACA LINCS 2: iPSCs LINCS 2: Differentiated Cells LINCS 2: Small molecules LINCS 2: Embryonic Stem Cells Plus 5 more...	None	RDA Covid-19 WG Resources LINCS Project
LINCS Extended Metadata Standard: Proteins	LINCS 2: Proteins	Standard	Life Science	Gene expression data Reaction data Catalytic activity Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 2: Embryonic Stem Cells LINCS 2: iPSCs LINCS 2: Small molecules LINCS 2: Other Reagents LINCS 2: Primary Cells Plus 4 more...	None	RDA Covid-19 WG Resources LINCS Project
LINCS Extended Metadata Standard: Small molecules	LINCS 2: Small molecules	Standard	Life Science	Gene expression data Reaction data Catalytic activity Cellular assay Small molecule	Homo sapiens	LINCS Data Portal	LINCS 2: iPSCs LINCS 2: Differentiated Cells LINCS 2: Primary Cells LINCS 2: Embryonic Stem Cells LINCS 2: Proteins Plus 5 more...	None	RDA Covid-19 WG Resources LINCS Project
~~LINCS Pilot Phase 1 Metadata Standards: Antibody Reagents~~	~~LINCS 1: Antibody Reagents~~	Standard	Life Science	Gene expression data Cellular assay	Homo sapiens	ImmPort LINCS Data Portal	LINCS 1: Small Molecules LINCS 1: Protein Reagents LINCS 1: Other Reagents LINCS 1: Primary Cells LINCS 1: Cell Lines Plus 1 more...	None	LINCS Project
~~LINCS Pilot Phase 1 Metadata Standards: Cell Lines~~	~~LINCS 1: Cell Lines~~	Standard	Life Science	Gene expression data Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 1: Small Molecules LINCS 1: Primary Cells LINCS 1: Antibody Reagents LINCS 1: Other Reagents LINCS 1: Protein Reagents Plus 1 more...	None	LINCS Project
~~LINCS Pilot Phase 1 Metadata Standards: Other Reagents~~	~~LINCS 1: Other Reagents~~	Standard	Life Science	Gene expression data Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 1: Small Molecules LINCS 1: Antibody Reagents LINCS 1: Protein Reagents LINCS 1: Primary Cells LINCS 1: Cell Lines Plus 1 more...	None	LINCS Project
~~LINCS Pilot Phase 1 Metadata Standards: Primary Cells~~	~~LINCS 1: Primary Cells~~	Standard	Life Science	Gene expression data Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 1: Small Molecules LINCS 1: Antibody Reagents LINCS 1: Other Reagents LINCS 1: Protein Reagents LINCS 1: Cell Lines Plus 1 more...	None	LINCS Project
~~LINCS Pilot Phase 1 Metadata Standards: Protein Reagents~~	~~LINCS 1: Protein Reagents~~	Standard	Life Science	Gene expression data Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 1: Antibody Reagents LINCS 1: Other Reagents LINCS 1: Primary Cells LINCS 1: Cell Lines LINCS 1: Small Molecules Plus 1 more...	None	LINCS Project
~~LINCS Pilot Phase 1 Metadata Standards: RNAi Reagents~~	~~LINCS 1: RNAi Reagents~~	Standard	Life Science	Gene expression data Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 1: Other Reagents LINCS 1: Cell Lines LINCS 1: Primary Cells LINCS 1: Small Molecules LINCS 1: Protein Reagents Plus 1 more...	None	LINCS Project
~~LINCS Pilot Phase 1 Metadata Standards: Small Molecules~~	~~LINCS 1: Small Molecules~~	Standard	Life Science	Gene expression data Cellular assay	Homo sapiens	LINCS Data Portal	LINCS 1: Antibody Reagents LINCS 1: Other Reagents LINCS 1: Primary Cells LINCS 1: Cell Lines LINCS 1: Protein Reagents Plus 1 more...	None	LINCS Project

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