bsg-c000018
Image for LINCS Project  LINCS Project
The LINCS project is based on the premise that disrupting any one of the many steps of a given biological process will cause related changes in the molecular and cellular characteristics, behavior, and/or function of the cell – the observable composite of which is known as the cellular phenotype. Observing how and when a cell’s phenotype is altered by specific stressors can provide clues about the underlying mechanisms involved in perturbation and ultimately, disease. In LINCS Production Phase II, the LINCS Data Working Group (DWG) is currently developing extended metadata specifications describing LINCS reagents, assays and experiments. Annotations for the perturbagens (small molecules, siRNA, growth factors and other ligands), cells, and some elements of experimental metadata should be common between all LINCS Centers. This will facilitate development of data analysis, formatting, and visualization strategies by LINCS investigators, and also the development of databases and data repositories in which to store and share LINCS data. This collection contains records for all LINCS resources associated with the project.

This record is maintained by: cchung   ORCID

Record added: April 27, 2016, 2:24 p.m..
Record updated: June 1, 2017, 12:09 p.m. by The FAIRsharing Team.

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18 records in view

Registry Name Abbreviation Type Domain Taxonomy Related Database Related Standard Related Policy In Collection/Recommendation Status

Library of Integrated Network-Based Cellular Signatures Data Portal LINCS Data Portal Database None ready

LINCS Extended Metadata Standard: Antibody Reagents LINCS 2: Antibody Reagents Standard None ready

LINCS Extended Metadata Standard: Cell lines LINCS 2: Cell lines Standard None ready

LINCS Extended Metadata Standard: Differentiated Cells LINCS 2: Differentiated Cells Standard None ready

LINCS Extended Metadata Standard: Embryonic Stem Cells LINCS 2: Embryonic Stem Cells Standard None ready

LINCS Extended Metadata Standard: Induced Pluripotent Stem Cells LINCS 2: iPSCs Standard None ready

LINCS Extended Metadata Standard: Nucleic Acid Reagents LINCS 2: Nucleic Acid Reagents Standard None ready

LINCS Extended Metadata Standard: Other Reagents LINCS 2: Other Reagents Standard None ready

LINCS Extended Metadata Standard: Primary Cells LINCS 2: Primary Cells Standard None ready

LINCS Extended Metadata Standard: Proteins LINCS 2: Proteins Standard None ready

LINCS Extended Metadata Standard: Small molecules LINCS 2: Small molecules Standard None ready

LINCS Pilot Phase 1 Metadata Standards: Antibody Reagents LINCS 1: Antibody Reagents Standard None deprecated

LINCS Pilot Phase 1 Metadata Standards: Cell Lines LINCS 1: Cell Lines Standard None deprecated

LINCS Pilot Phase 1 Metadata Standards: Other Reagents LINCS 1: Other Reagents Standard None deprecated

LINCS Pilot Phase 1 Metadata Standards: Primary Cells LINCS 1: Primary Cells Standard None deprecated

LINCS Pilot Phase 1 Metadata Standards: Protein Reagents LINCS 1: Protein Reagents Standard None deprecated

LINCS Pilot Phase 1 Metadata Standards: RNAi Reagents LINCS 1: RNAi Reagents Standard None deprecated

LINCS Pilot Phase 1 Metadata Standards: Small Molecules LINCS 1: Small Molecules Standard None deprecated